Vector manometry and LOS dynamics
- Academic Department of Surgery and Gastrointestinal Physiology Unit
- The Royal London Hospital
- Whitechapel
- London E1 1BB, UK
- Dr Jenkinson email:ajenkin235{at}aol.com
Editor,—We read with interest the recent paper by Kahrilas et al on the effect of hiatus hernia on gastro-oesophageal junction pressure (Gut1999;44:476–482). These authors used a novel technique that combined vector manometry, fluoroscopy, and endoscopic tagging of anatomical landmarks to map the differences in pressure profile between patients with and without hiatus hernia. Analysis of the vector profiles, taken at end expiration, revealed two distinct high pressure zones in each of the seven patients with hiatus hernia. These were thought to represent an axial separation of the internal and external components of the lower oesophageal sphincter (LOS). When these high pressure zones were repositioned …
