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[Front cover][Table of contents PDF]

Leading articles

  • The molecular genetics of familial intrahepatic cholestasis

    • P L M JANSEN,
    • M MÜLLER
    Gut 2000;47:1 1-5 doi:10.1136/gut.47.1.1

  • Inducible nitric oxide synthase: a little bit of good in all of us

    • P KUBES
    Gut 2000;47:1 6-9 doi:10.1136/gut.47.1.6

Commentaries

  • H pylori and Lewis antigens

    • B J APPELMELK,
    • C M J E VANDENBROUCKE-GRAULS
    Gut 2000;47:1 10-11 doi:10.1136/gut.47.1.10

  • A little rest and relaxation

    • J TACK,
    • D SIFRIM
    Gut 2000;47:1 11-12 doi:10.1136/gut.47.1.11

  • MMPs in the gut: inflammation hits the matrix

    • D SCHUPPAN,
    • E G HAHN
    Gut 2000;47:1 12-14 doi:10.1136/gut.47.1.12

  • Heparin and inflammation: a new use for an old GAG?

    • M PERRETTI,
    • C P PAGE
    Gut 2000;47:1 14-15 doi:10.1136/gut.47.1.14

Science alert

  • Antimicrobial peptides in innate intestinal host defence

    • R N CUNLIFFE,
    • Y R MAHIDA
    Gut 2000;47:1 16-17 doi:10.1136/gut.47.1.16

Helicobacter pylori

  • Association of peptic ulcer with increased expression of Lewis antigens but not cagA, iceA, andvacA in Helicobacter pylori isolates in an Asian population

    • P Y Zheng,
    • J Hua,
    • K G Yeoh,
    • B Ho
    Gut 2000;47:1 18-22 doi:10.1136/gut.47.1.18

  • High prevalence of potentially virulent strains ofHelicobacter pylori in the general male British population

    • J Danesh,
    • P Whincup,
    • M Walker,
    • L Lennon,
    • A Thomson,
    • P Appleby,
    • C Hawkey,
    • J C Atherton
    Gut 2000;47:1 23-25 doi:10.1136/gut.47.1.23

Motility

  • No relation between body mass and gastro-oesophageal reflux symptoms in a Swedish population based study

    • J Lagergren,
    • R Bergström,
    • O Nyrén
    Gut 2000;47:1 26-29 doi:10.1136/gut.47.1.26

  • Effect of atropine on proximal gastric motor and sensory function in normal subjects

    • I Lidums,
    • G S Hebbard,
    • R H Holloway
    Gut 2000;47:1 30-36 doi:10.1136/gut.47.1.30

Cancer

  • DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer

    • H Iino,
    • L Simms,
    • J Young,
    • J Arnold,
    • I M Winship,
    • S I Webb,
    • K L Furlong,
    • B Leggett,
    • J R Jass
    Gut 2000;47:1 37-42 doi:10.1136/gut.47.1.37

  • Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum

    • J R Jass,
    • H Iino,
    • A Ruszkiewicz,
    • D Painter,
    • M J Solomon,
    • D J Koorey,
    • D Cohn,
    • K L Furlong,
    • M D Walsh,
    • J Palazzo,
    • T Bocker Edmonston,
    • R Fishel,
    • J Young,
    • B A Leggett
    Gut 2000;47:1 43-49 doi:10.1136/gut.47.1.43

Inflammation and inflammatory bowel disease

  • Increased expression of collagenase-3 (MMP-13) and MT1-MMP in oesophageal cancer is related to cancer aggressiveness

    • T Etoh,
    • H Inoue,
    • Y Yoshikawa,
    • G F Barnard,
    • S Kitano,
    • M Mori
    Gut 2000;47:1 50-56 doi:10.1136/gut.47.1.50

  • Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease

    • R B Heuschkel,
    • T T MacDonald,
    • G Monteleone,
    • M Bajaj-Elliott,
    • J A Walker Smith,
    • S L F Pender
    Gut 2000;47:1 57-62 doi:10.1136/gut.47.1.57

  • Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease

    • B von Lampe,
    • B Barthel,
    • S E Coupland,
    • E-O Riecken,
    • S Rosewicz
    Gut 2000;47:1 63-73 doi:10.1136/gut.47.1.63

  • Antineutrophil antibodies associated with ulcerative colitis interact with the antigen(s) during the process of apoptosis

    • J Mallolas,
    • M Esteve,
    • E Rius,
    • E Cabré,
    • M A Gassull
    Gut 2000;47:1 74-78 doi:10.1136/gut.47.1.74

  • Non-pathogenic bacteria elicit a differential cytokine response by intestinal epithelial cell/leucocyte co-cultures

    • D Haller,
    • C Bode,
    • W P Hammes,
    • A M A Pfeifer,
    • E J Schiffrin,
    • S Blum
    Gut 2000;47:1 79-87 doi:10.1136/gut.47.1.79

  • Heparin attenuates TNF-α induced inflammatory response through a CD11b dependent mechanism

    • A Salas,
    • M Sans,
    • A Soriano,
    • J C Reverter,
    • D C Anderson,
    • J M Piqué,
    • J Panés
    Gut 2000;47:1 88-96 doi:10.1136/gut.47.1.88

  • Blockade of the integrin αLβ2 but not of integrins α4 and/or β7 significantly prolongs intestinal allograft survival in mice

    • S Sarnacki,
    • F Auber,
    • C Crétolle,
    • C Camby,
    • M Cavazzana-Calvo,
    • W Müller,
    • N Wagner,
    • N Brousse,
    • Y Révillon,
    • A Fischer,
    • N Cerf-Bensussan
    Gut 2000;47:1 97-104 doi:10.1136/gut.47.1.97

Epithelial proliferation and imaging

  • Role of urokinase and its receptor in basal and stimulated colonic epithelial cell migration in vitro

    • A J Wilson,
    • P R Gibson
    Gut 2000;47:1 105-111 doi:10.1136/gut.47.1.105

  • Glucagon-like peptide-2 enhances intestinal epithelial barrier function of both transcellular and paracellular pathways in the mouse

    • M A Benjamin,
    • D M McKay,
    • P-C Yang,
    • H Cameron,
    • M H Perdue
    Gut 2000;47:1 112-119 doi:10.1136/gut.47.1.112

  • Evaluation of prognosis of squamous cell carcinoma of the oesophagus by endoscopic ultrasonography

    • M Shinkai,
    • Y Niwa,
    • T Arisawa,
    • N Ohmiya,
    • H Goto,
    • T Hayakawa
    Gut 2000;47:1 120-125 doi:10.1136/gut.47.1.120

  • Diagnostic accuracy and interobserver agreement of CT colonography (virtual colonoscopy)

    • P Pescatore,
    • T Glücker,
    • J Delarive,
    • R Meuli,
    • D Pantoflickova,
    • B Duvoisin,
    • P Schnyder,
    • A L Blum,
    • G Dorta
    Gut 2000;47:1 126-130 doi:10.1136/gut.47.1.126

Liver and biliary disease

  • Hepatitis C virus related cirrhosis: time to occurrence of hepatocellular carcinoma and death

    • F Degos,
    • C Christidis,
    • N Ganne-Carrie,
    • J-P Farmachidi,
    • C Degott,
    • C Guettier,
    • J-C Trinchet,
    • M Beaugrand,
    • S Chevret
    Gut 2000;47:1 131-136 doi:10.1136/gut.47.1.131

  • Cytotoxic T lymphocyte responses and CTL epitope escape mutation in HBsAg, anti-HBe positive individuals

    • S I Khakoo,
    • R Ling,
    • I Scott,
    • A I Dodi,
    • T J Harrison,
    • G M Dusheiko,
    • J A Madrigal
    Gut 2000;47:1 137-143 doi:10.1136/gut.47.1.137

  • Insulin and gall stones: a population case control study in southern Italy

    • G Misciagna,
    • V Guerra,
    • A Di Leo,
    • M Correale,
    • M Trevisan
    Gut 2000;47:1 144-147 doi:10.1136/gut.47.1.144

Review

  • DNA mismatch repair genes and colorectal cancer

    • J M D WHEELER,
    • W F BODMER,
    • J M D WHEELER,
    • N J McC MORTENSEN
    Gut 2000;47:1 148-153 doi:10.1136/gut.47.1.148

Letters to the editor

  • Differential expression of cyclooxygenase 2 in human colorectal cancer

    • M HULL,
    • M LANGMAN
    1. Commentator:
      • J DIMBERG and
      • P SÖDERKVIST
    Gut 2000;47:1 154 doi:10.1136/gut.47.1.154

  • Proton pump inhibitors for Barrett's oesophagus

    • F T M PETERS
    Gut 2000;47:1 154-155 doi:10.1136/gut.47.1.154a

  • MCP-3 in inflammatory bowel disease

    • U HELWIG,
    • K M LAMMERS,
    • P GIONCHETTI,
    • F RIZZELLO,
    • M CAMPIERI,
    • M UGUCCIONI
    1. Commentator:
      • J WEDEMEYER,
      • A LORENTZ,
      • M P MANNS,
      • and S C BISCHOFF
    Gut 2000;47:1 155 doi:10.1136/gut.47.1.155

  • One minute unbuffered urease test: should it be read at 10 minutes?

    • S SENGUPTA,
    • G CROSTHWAITE
    Gut 2000;47:1 155-156 doi:10.1136/gut.47.1.155a

  • Thalidomide treatment of oesophageal ulceration

    • J RYAN
    Gut 2000;47:1 156 doi:10.1136/gut.47.1.156

  • Use of Doppler ultrasound in Crohn's disease

    • J A VAN OOSTAYEN,
    • M N J M WASSER
    Gut 2000;47:1 156 doi:10.1136/gut.47.1.156a

  • Percutaneous drainage of echinococcal cysts (PAIR—puncture, aspiration, injection, reaspiration): results of a worldwide survey for assessment of its safety and efficacy

    • C FÌLICE,
    • E BRUNETTI,
    • R BRUNO,
    • F G CRIPPA,
    • WHO-INFORMAL WORKING GROUP ON ECHINOCOCCOSIS-PAIR NETWORK
    1. Commentator:
      • D L MORRIS
    Gut 2000;47:1 156-157 doi:10.1136/gut.47.1.156b

Book review

  • Mucosal T cells. Chemical Immunology. Vol 71.

    • A J S MACPHERSON
    Gut 2000;47:1 157 doi:10.1136/gut.47.1.157

  • Gastrointestinal Endosonography.

    • L PALAZZO
    Gut 2000;47:1 157 doi:10.1136/gut.47.1.157a

  • An Atlas of Diagnostic Radiology in Gastroenterology

    • IAN FORGACS
    Gut 2000;47:1 157 doi:10.1136/gut.47.1.157b

Correction

  • Correction for vol. 46, p. 534

    Gut 2000;47:1 157

  • Correction for vol. 46, p. 701

    Gut 2000;47:1 157

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