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Gut 47:787-791 doi:10.1136/gut.47.6.787
  • Inflammation and inflammatory bowel disease

Genetic analyses of chromosome 12 loci in Crohn's disease

Table 2

Results and power of the previously published linkage analyses on chromosome 12 for Crohn's disease (CD) families

Author No of multiplex CD families No of affected relative pairs Results (p value of the test)
Satsangi et al 9 67 81 3×10−7
Duerr et al 10 80 127 0.0002
Yanget al 11 48 75 0.0004
Curran et al 7 134 167 0.005
Choet al 20 99 175 0.40
Brant et al 21 77 148 0.30
Riouxet al 22 114 0.24
Present study 95 157 0.35

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