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Gut 48:418-424 doi:10.1136/gut.48.3.418
  • Coeliac disease

FAS engagement drives apoptosis of enterocytes of coeliac patients

Table 2

Overall representation of the characteristics of the mucosal manifestations in organ culture of the small intestine of coeliac disease (CD) patients and controls

Untreated CD
Villus atrophy Normal mucosa Treated CD Controls
Increase in enterocyte apoptosis2-150 Yes No No No
Increase in enterocyte Ki67 expression2-150 Yes No No No
Increase in enterocyte FAS expression2-150 Yes No Yes No
  • 2-150 Organ cultures with gliadin digestv cultures with medium alone.

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