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Issue information

[Front cover][Table of contents PDF]

Leading articles

  • Some of the challenges in drug development for irritable bowel syndrome

    • E A MAYER
    Gut 2001;48:5 585-586 doi:10.1136/gut.48.5.585

  • Dietary fibre and the risk of colorectal cancer

    • R A GOODLAD
    Gut 2001;48:5 587-589 doi:10.1136/gut.48.5.587

Commentaries

  • Helicobacter pylori, harmful to the brain?

    • A T BLEI
    Gut 2001;48:5 590-591 doi:10.1136/gut.48.5.590

  • Rational dosing of azathioprine and 6-mercaptopurine

    • W J SANDBORN
    Gut 2001;48:5 591-592 doi:10.1136/gut.48.5.591

  • New pouches for old?

    • N MORTENSEN
    Gut 2001;48:5 592-593 doi:10.1136/gut.48.5.592

Science alert

  • Landscaper seeks remunerative position

    • R J PLAYFORD
    Gut 2001;48:5 594-595 doi:10.1136/gut.48.5.594

Clinical alert

  • Serotonin receptor modulation in irritable bowel syndrome: one step forwards and one step backwards

    • P J WHORWELL
    Gut 2001;48:5 596-597 doi:10.1136/gut.48.5.596

Helicobacter pylori

  • Helicobacter pylori infection induced alteration of gene expression in human gastric cells

    • C-C Chiou,
    • C-C Chan,
    • D-L Sheu,
    • K-T Chen,
    • Y-S Li,
    • E-C Chan
    Gut 2001;48:5 598-604 doi:10.1136/gut.48.5.598

  • Helicobacter pylori infection induces hyperammonaemia in Mongolian gerbils with liver cirrhosis

    • H Suto,
    • T Azuma,
    • S Ito,
    • M Ohtani,
    • M Dojo,
    • Y Ito,
    • Y Kohli,
    • M Kuriyama
    Gut 2001;48:5 605-608 doi:10.1136/gut.48.5.605

Therapy update

  • Probiotics in inflamatory bowel disease

    • F Shanahan
    Gut 2001;48:5 609 doi:10.1136/gut.48.5.609

  • Antibiotics in Crohn's disease

    • J-F Colombel,
    • A Cortot,
    • H J van Kruiningen
    Gut 2001;48:5 647 doi:10.1136/gut.48.5.647

Inflammation and inflammatory bowel disease

  • Absence of endogenous interleukin 10 enhances early stress response during post-ischaemic injury in mice intestine

    • B Zingarelli,
    • Z Yang,
    • P W Hake,
    • A Denenberg,
    • H R Wong
    Gut 2001;48:5 610-622 doi:10.1136/gut.48.5.610

  • Upregulation of Reg 1α and GW112 in the epithelium of inflamed colonic mucosa

    • S Shinozaki,
    • T Nakamura,
    • M Iimura,
    • Y Kato,
    • B Iizuka,
    • M Kobayashi,
    • N Hayashi
    Gut 2001;48:5 623-629 doi:10.1136/gut.48.5.623

  • Role of mast cells in chronic stress induced colonic epithelial barrier dysfunction in the rat

    • J Santos,
    • P-C Yang,
    • J D Söderholm,
    • M Benjamin,
    • M H Perdue
    Gut 2001;48:5 630-636 doi:10.1136/gut.48.5.630

  • No evidence of persistent mumps virus infection in inflammatory bowel disease

    • M Iizuka,
    • H Saito,
    • M Yukawa,
    • H Itou,
    • T Shirasaka,
    • M Chiba,
    • T Fukushima,
    • S Watanabe
    Gut 2001;48:5 637-641 doi:10.1136/gut.48.5.637

  • Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease

    • C Cuffari,
    • S Hunt,
    • T Bayless
    Gut 2001;48:5 642-646 doi:10.1136/gut.48.5.642

Proliferation and cancer

  • Dramatic diurnal variation in the concentration of the human trefoil peptide TFF2 in gastric juice

    • J I Semple,
    • J L Newton,
    • B R Westley,
    • F E B May
    Gut 2001;48:5 648-655 doi:10.1136/gut.48.5.648

  • Genetic alterations and growth pattern in biliary duct carcinomas: loss of heterozygosity at chromosome 5q bears a close relation with polypoid growth

    • E Hidaka,
    • A Yanagisawa,
    • M Seki,
    • T Setoguchi,
    • Y Kato
    Gut 2001;48:5 656-659 doi:10.1136/gut.48.5.656

  • Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation

    • W A Brown,
    • S A Skinner,
    • C Malcontenti-Wilson,
    • D Vogiagis,
    • P E O'Brien
    Gut 2001;48:5 660-666 doi:10.1136/gut.48.5.660

  • Circumferential resection margin involvement: an independent predictor of survival following surgery for oesophageal cancer

    • S P L Dexter,
    • H Sue-Ling,
    • M J McMahon,
    • P Quirke,
    • N Mapstone,
    • I G Martin
    Gut 2001;48:5 667-670 doi:10.1136/gut.48.5.667

Motility and visceral sensation

  • Analysis of the RET,GDNF, EDN3, andEDNRB genes in patients with intestinal neuronal dysplasia and Hirschsprung disease

    • R Gath,
    • A Goessling,
    • K-M Keller,
    • S Koletzko,
    • W Coerdt,
    • H Müntefering,
    • S Wirth,
    • R M W Hofstra,
    • L Mulligan,
    • C Eng,
    • A von Deimling
    Gut 2001;48:5 671-675 doi:10.1136/gut.48.5.671

  • Effects of octreotide on responses to colorectal distension in the rat

    • X Su,
    • M B Burton,
    • G F Gebhart
    Gut 2001;48:5 676-682 doi:10.1136/gut.48.5.676

  • Functional results and visceral perception after ileo neo-rectal anastomosis in patients: a pilot study

    • G I Andriesse,
    • H G Gooszen,
    • M E I Schipper,
    • L M A Akkermans,
    • T J M V van Vroonhoven,
    • C J H M van Laarhoven
    Gut 2001;48:5 683-689 doi:10.1136/gut.48.5.683

  • Modification of small bowel mechanosensitivity by intestinal fat

    • A M Accarino,
    • F Azpiroz,
    • J-R Malagelada
    Gut 2001;48:5 690-695 doi:10.1136/gut.48.5.690

Coeliac disease

  • Candidate gene regions and genetic heterogeneity in gluten sensitivity

    • P Holopainen,
    • K Mustalahti,
    • P Uimari,
    • P Collin,
    • M Mäki,
    • J Partanen
    Gut 2001;48:5 696-701 doi:10.1136/gut.48.5.696

Gallstones

  • Biliary lipid composition in cholesterol microlithiasis

    • M Fracchia,
    • S Pellegrino,
    • P Secreto,
    • L Gallo,
    • G Masoero,
    • A Pera,
    • G Galatola
    Gut 2001;48:5 702-706 doi:10.1136/gut.48.5.702

Liver disease

  • The epidemiology of hepatitis C in a UK health regional population of 5.12 million

    • A H Mohsen,
    • Trent HCV Study Group
    Gut 2001;48:5 707-713 doi:10.1136/gut.48.5.707

  • Low frequency of HLA-DRB1*11 in hepatitis C virus induced end stage liver disease

    • H L Tillmann,
    • D-F Chen,
    • C Trautwein,
    • V Kliem,
    • A Grundey,
    • A Berning-Haag,
    • K Böker,
    • S Kubicka,
    • L Pastucha,
    • W Stangel,
    • M P Manns
    Gut 2001;48:5 714-718 doi:10.1136/gut.48.5.714

Case reports

  • Heterotopic gastric mucosa together with intestinal metaplasia and moderate dysplasia in the gall bladder: report of two clinically unusual cases with literature review

    • N Xeropotamos,
    • A S Skopelitou,
    • Ch Batsis,
    • A M Kappas
    Gut 2001;48:5 719-723 doi:10.1136/gut.48.5.719

  • Distinct outcomes of chloride diarrhoea in two siblings with identical genetic background of the disease: implications for early diagnosis and treatment

    • P Höglund,
    • C Holmberg,
    • P Sherman,
    • J Kere
    Gut 2001;48:5 724-727 doi:10.1136/gut.48.5.724

  • A winking anus may signify spinal injury

    • A J MALOUF,
    • M A KAMM
    Gut 2001;48:5 728-729 doi:10.1136/gut.48.5.728

Occasional viewpoint

  • Persistent low prevalence of Western digestive diseases in Africa: confounding aetiological factors

    • I SEGAL,
    • A R P WALKER,
    • A WADEE
    Gut 2001;48:5 730-732 doi:10.1136/gut.48.5.730

Review

  • The promise and potential hazards of adenovirus gene therapy

    • L S YOUNG,
    • V MAUTNER
    Gut 2001;48:5 733-736 doi:10.1136/gut.48.5.733

Letters to the editor

  • Grading system for inflammation in ulcerative colitis

    • S S CROSS
    1. Commentator:
      • K GEBOES,
      • R RIDDELL,
      • A ÖST,
      • B JENSFELT,
      • T PERSSON,
      • and R LÖFBERG
    Gut 2001;48:5 737 doi:10.1136/gut.48.5.737

  • Insulin and gall stones

    • K W HEATON,
    • P M EMMETT
    1. Commentator:
      • G MISCIAGNA and
      • M TREVISAN
    Gut 2001;48:5 737-738 doi:10.1136/gut.48.5.737a

  • Heparin as an anti-inflammatory agent: it's no GAG to forget about chemokines

    • S J CONNOR,
    • M C GRIMM
    Gut 2001;48:5 738 doi:10.1136/gut.48.5.738

  • Management of variceal haemorrhage in cirrhotic patients

    • A K BURROUGHS,
    • D W PATCH
    1. Commentator:
      • R JALAN and
      • P C HAYES
    Gut 2001;48:5 738-740 doi:10.1136/gut.48.5.738a

  • Long term follow up of interferon responder children with chronic hepatitis B

    • N KOÇAK,
    • I N SALTIK,
    • H ÖZEN,
    • F GÜRAKAN,
    • A YÜCE
    Gut 2001;48:5 740 doi:10.1136/gut.48.5.740

  • Renal sodium handling in preascitic cirrhosis

    • G SANSOÈ,
    • A FERRARI
    1. Commentator:
      • J CLÀRIA and
      • J RODÉS
    Gut 2001;48:5 740-741 doi:10.1136/gut.48.5.740a

Book review

  • Comprehensive Clinical Hepatology.

    • D H ADAMS
    Gut 2001;48:5 741 doi:10.1136/gut.48.5.741

  • Atlas of Gastroenterology

    • S CAIRNS
    Gut 2001;48:5 741 doi:10.1136/gut.48.5.741a

  • Endoscopic Gastric Surgery.

    • R C MASON
    Gut 2001;48:5 741 doi:10.1136/gut.48.5.741b

Correction

  • Correction for vol. 48, p. 68

    Gut 2001;48:5 741

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