Effects of a motilin receptor agonist (ABT-229) on upper gastrointestinal symptoms in type 1 diabetes mellitus: a randomised, double blind, placebo controlled trial

N J Talley; M Verlinden; D J Geenen; R B Hogan; D Riff; R W McCallum; R J Mack

doi:10.1136/gut.49.3.395

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Effects of a motilin receptor agonist (ABT-229) on upper gastrointestinal symptoms in type 1 diabetes mellitus: a randomised, double blind, placebo controlled trial

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	Abstract	Full	Pdf
Aug 2001	70	58	35
Sep 2001	38	62	31
Oct 2001	14	52	27
Nov 2001	11	44	11
Dec 2001	6	15	6
Jan 2002	10	28	14
Feb 2002	7	21	12
Mar 2002	23	31	17
Apr 2002	3	30	7
May 2002	8	28	13
Jun 2002	0	34	12
Jul 2002	2	15	8
Aug 2002	4	17	8
Sep 2002	5	9	5
Oct 2002	9	22	9
Nov 2002	5	16	10
Dec 2002	6	5	1
Jan 2003	1	18	9
Feb 2003	6	18	3
Mar 2003	5	19	5
Apr 2003	6	19	6
May 2003	19	21	9
Jun 2003	10	15	7
Jul 2003	21	19	2
Aug 2003	13	12	4
Sep 2003	27	24	10
Oct 2003	24	21	10
Nov 2003	26	12	2
Dec 2003	18	24	3
Jan 2004	38	20	3
Feb 2004	22	20	15
Mar 2004	33	25	8
Apr 2004	26	10	9
May 2004	71	54	10
Jun 2004	82	65	9
Jul 2004	86	90	13
Aug 2004	37	89	11
Sep 2004	45	99	33
Oct 2004	24	49	14
Nov 2004	18	76	24
Dec 2004	15	47	16
Jan 2005	22	70	27
Feb 2005	12	77	24
Mar 2005	16	42	34
Apr 2005	13	42	25
May 2005	16	42	18
Jun 2005	5	16	10
Jul 2005	18	35	29
Aug 2005	22	51	28
Sep 2005	26	50	28
Oct 2005	20	54	16
Nov 2005	19	57	20
Dec 2005	22	60	28
Jan 2006	17	42	15
Feb 2006	18	45	19
Mar 2006	9	30	16
Apr 2006	14	51	13
May 2006	17	29	14
Jun 2006	17	31	18
Jul 2006	13	23	13
Aug 2006	12	28	10
Sep 2006	19	33	13
Oct 2006	18	34	10
Nov 2006	22	50	18
Dec 2006	10	26	7
Jan 2007	12	46	15
Feb 2007	9	36	20
Mar 2007	32	38	23
Apr 2007	21	8	6
May 2007	17	5	3
Jun 2007	33	6	5
Jul 2007	23	9	9
Aug 2007	35	8	11
Sep 2007	25	20	8
Oct 2007	38	14	11
Nov 2007	12	6	5
Dec 2007	16	2	4
Jan 2008	13	4	5
Feb 2008	19	3	4
Mar 2008	16	4	11
Apr 2008	23	2	4
May 2008	9	3	2
Jun 2008	17	2	4
Jul 2008	23	8	10
Aug 2008	18	4	2
Sep 2008	12	4	3
Oct 2008	22	4	2
Nov 2008	16	1	1
Dec 2008	9	5	8
Jan 2009	19	2	0
Feb 2009	27	3	5
Mar 2009	16	3	3
Apr 2009	17	0	2
May 2009	13	3	1
Jun 2009	11	2	0
Jul 2009	13	3	3
Aug 2009	14	2	0
Sep 2009	22	3	4
Oct 2009	36	2	5
Nov 2009	47	1	2
Dec 2009	20	0	1
Jan 2010	12	3	2
Feb 2010	21	5	3
Mar 2010	49	6	13
Apr 2010	32	5	5
May 2010	39	4	6
Jun 2010	30	6	6
Jul 2010	10	1	4
Aug 2010	24	4	2
Sep 2010	20	1	4
Oct 2010	31	9	5
Nov 2010	24	3	3
Dec 2010	28	3	2
Jan 2011	14	9	2
Feb 2011	26	1	2
Mar 2011	23	2	0
Apr 2011	19	6	0
May 2011	22	4	4
Jun 2011	19	0	0
Jul 2011	22	8	7
Aug 2011	26	7	4
Sep 2011	25	1	2
Oct 2011	34	5	0
Nov 2011	19	6	4
Dec 2011	29	14	8
Jan 2012	23	28	8
Feb 2012	26	19	6
Mar 2012	33	22	8
Apr 2012	24	13	8
May 2012	15	8	11
Jun 2012	14	24	4
Jul 2012	22	9	9
Aug 2012	16	25	14
Sep 2012	11	13	6
Oct 2012	17	18	15
Nov 2012	19	24	18
Dec 2012	21	14	12
Jan 2013	20	13	6
Feb 2013	27	22	9
Mar 2013	49	20	14
Apr 2013	36	21	15
May 2013	31	14	12
Jun 2013	9	10	1
Jul 2013	19	8	10
Aug 2013	11	10	3
Sep 2013	14	11	2
Oct 2013	10	16	5
Nov 2013	23	19	8
Dec 2013	13	2	12
Jan 2014	11	10	8
Feb 2014	15	6	5
Mar 2014	14	5	5
Apr 2014	16	9	5
May 2014	15	9	5
Jun 2014	14	13	3
Jul 2014	32	10	2
Aug 2014	11	11	7
Sep 2014	19	10	10
Oct 2014	16	18	5
Nov 2014	13	15	3
Dec 2014	3	13	8
Jan 2015	11	15	0
Feb 2015	6	1	2
Mar 2015	10	15	2
Apr 2015	14	3	5
May 2015	7	19	2
Jun 2015	7	7	5
Jul 2015	6	12	5
Aug 2015	6	5	2
Sep 2015	19	4	0
Oct 2015	3	6	2
Nov 2015	11	9	3
Dec 2015	7	5	5
Jan 2016	8	6	1
Feb 2016	8	6	0
Mar 2016	10	4	3
Apr 2016	5	16	1
May 2016	7	10	1
Jun 2016	14	7	0
Jul 2016	13	11	2
Aug 2016	17	8	3
Sep 2016	18	6	2
Oct 2016	20	13	7
Nov 2016	25	9	9
Dec 2016	28	8	1
Jan 2017	16	8	4
Feb 2017	3	7	2
Mar 2017	4	9	3
Apr 2017	4	18	4
May 2017	7	26	9
Jun 2017	8	13	0
Jul 2017	22	21	3
Aug 2017	28	24	1
Sep 2017	29	22	1
Oct 2017	26	22	1
Nov 2017	23	19	0
Dec 2017	21	17	1
Jan 2018	24	18	3
Feb 2018	26	22	0
Mar 2018	32	22	4
Apr 2018	37	27	0
May 2018	26	24	0
Jun 2018	32	30	0
Jul 2018	14	10	0
Aug 2018	8	6	2
Sep 2018	27	15	4
Oct 2018	71	69	1
Nov 2018	75	69	8
Dec 2018	65	61	0
Jan 2019	57	53	2
Feb 2019	56	51	4
Mar 2019	22	20	7
Apr 2019	13	13	9
May 2019	6	6	5
Jun 2019	9	9	4
Jul 2019	9	7	6
Aug 2019	7	5	6
Sep 2019	13	11	10
Oct 2019	9	5	3
Nov 2019	17	10	9
Dec 2019	19	12	2
Jan 2020	13	5	2
Feb 2020	12	4	12
Mar 2020	17	7	5
Apr 2020	10	8	4
May 2020	38	19	8
Jun 2020	17	9	3
Jul 2020	13	11	5
Aug 2020	14	14	3
Sep 2020	27	21	7
Oct 2020	23	17	8
Nov 2020	17	11	6
Dec 2020	32	22	9
Jan 2021	25	18	5
Feb 2021	7	7	3
Mar 2021	11	9	2
Apr 2021	32	18	16
May 2021	16	16	2
Jun 2021	8	8	3
Jul 2021	13	13	16
Aug 2021	7	6	9
Sep 2021	8	8	3
Oct 2021	22	20	20
Nov 2021	24	20	22
Dec 2021	101	97	4
Jan 2022	67	80	20
Feb 2022	17	11	6
Mar 2022	22	18	4
Apr 2022	34	26	5
May 2022	28	28	18
Jun 2022	27	27	6
Jul 2022	24	18	4
Aug 2022	42	40	5
Sep 2022	31	30	15
Oct 2022	47	43	10
Nov 2022	23	23	9
Dec 2022	27	22	3
Jan 2023	17	17	6
Feb 2023	38	34	3
Mar 2023	26	22	3
Apr 2023	26	25	4
May 2023	21	17	7
Jun 2023	28	16	4
Jul 2023	16	14	10
Aug 2023	18	12	5
Sep 2023	57	55	7
Oct 2023	84	82	3
Nov 2023	38	38	0
Dec 2023	184	22	2
Jan 2024	81	1	2
Feb 2024	88	1	0
Mar 2024	92	5	1
Total	6151	5363	2006

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