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Gut 49:629-635 doi:10.1136/gut.49.5.629
  • Helicobacter pylori

Analysis of iceA genotypes in South African Helicobacter pylori strains and relationship to clinically significant disease

Table 2

Distribution of vacA/iceA alleles in single genotype isolates (n (%))

Allele Gastritis (n=22) PUD (n=17) GC
(n=15)
vacAs1/iceA1 2  (9) 8  (47)2-150 10  (67)2-165
vacAs1/iceA2BC 3 (14) 3 (18) 4 (26)
vacAs1/iceA2D 3 (14) 6 (35) 1 (7)
vacAs2/iceA1 1 (5) 0 (0) 0 (0)
vacAs2/iceA2BC 10 (45) 0 (0)2-160 0 (0)2-160
vacAs2/iceA2D 3 (14) 0 (0) 0 (0)
  • PUD, peptic ulcer disease; GC, gastric adenocarcinoma.

  • 2-150 p<0.01,

  • 2-160 p<0.002,

  • 2-165 p<0.0005 versus gastritis.

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