Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses

W Kruis; S Schreiber; D Theuer; J-W Brandes; E Schütz; S Howaldt; B Krakamp; J Hämling; H Mönnikes; I Koop; M Stolte; D Pallant; U Ewald

doi:10.1136/gut.49.6.783

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Inflammation and inflammatory bowel disease

Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses

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	Abstract	Full	Pdf
Nov 2001	132	136	54
Dec 2001	117	121	52
Jan 2002	31	81	18
Feb 2002	23	84	27
Mar 2002	18	45	26
Apr 2002	12	44	17
May 2002	11	23	19
Jun 2002	3	36	13
Jul 2002	4	33	6
Aug 2002	8	35	9
Sep 2002	23	30	17
Oct 2002	11	29	13
Nov 2002	11	24	16
Dec 2002	8	9	7
Jan 2003	8	26	13
Feb 2003	2	13	11
Mar 2003	7	11	5
Apr 2003	5	23	11
May 2003	5	24	9
Jun 2003	3	15	11
Jul 2003	9	19	7
Aug 2003	13	12	8
Sep 2003	10	23	14
Oct 2003	16	14	3
Nov 2003	26	15	12
Dec 2003	21	42	7
Jan 2004	26	14	11
Feb 2004	24	19	6
Mar 2004	19	24	12
Apr 2004	28	34	8
May 2004	37	36	13
Jun 2004	48	48	15
Jul 2004	40	46	12
Aug 2004	20	35	10
Sep 2004	24	52	28
Oct 2004	10	34	8
Nov 2004	8	60	14
Dec 2004	11	32	4
Jan 2005	12	36	33
Feb 2005	14	21	14
Mar 2005	13	36	19
Apr 2005	1	31	7
May 2005	4	39	28
Jun 2005	19	39	28
Jul 2005	7	30	20
Aug 2005	11	19	24
Sep 2005	11	24	10
Oct 2005	10	29	15
Nov 2005	17	29	23
Dec 2005	15	34	14
Jan 2006	14	26	22
Feb 2006	10	16	13
Mar 2006	10	26	24
Apr 2006	9	21	12
May 2006	11	20	19
Jun 2006	8	23	15
Jul 2006	9	29	16
Aug 2006	17	10	5
Sep 2006	17	20	11
Oct 2006	13	27	20
Nov 2006	17	15	17
Dec 2006	11	28	14
Jan 2007	6	21	13
Feb 2007	7	22	16
Mar 2007	5	24	17
Apr 2007	9	8	6
May 2007	26	9	7
Jun 2007	8	9	12
Jul 2007	11	9	9
Aug 2007	15	3	1
Sep 2007	11	7	5
Oct 2007	13	4	11
Nov 2007	22	9	10
Dec 2007	13	4	2
Jan 2008	10	0	2
Feb 2008	15	4	6
Mar 2008	19	9	6
Apr 2008	14	6	8
May 2008	11	4	2
Jun 2008	18	5	2
Jul 2008	21	0	2
Aug 2008	15	1	1
Sep 2008	30	0	1
Oct 2008	25	3	2
Nov 2008	18	1	3
Dec 2008	6	2	1
Jan 2009	15	2	0
Feb 2009	22	2	3
Mar 2009	8	2	3
Apr 2009	9	4	8
May 2009	10	8	9
Jun 2009	11	4	6
Jul 2009	12	3	2
Aug 2009	10	3	2
Sep 2009	17	3	1
Oct 2009	22	5	6
Nov 2009	27	2	6
Dec 2009	12	2	2
Jan 2010	20	1	2
Feb 2010	7	6	3
Mar 2010	25	8	4
Apr 2010	14	4	1
May 2010	10	5	1
Jun 2010	22	7	4
Jul 2010	16	4	5
Aug 2010	16	2	3
Sep 2010	19	6	7
Oct 2010	21	6	3
Nov 2010	23	1	3
Dec 2010	11	8	5
Jan 2011	15	1	2
Feb 2011	9	2	2
Mar 2011	15	2	3
Apr 2011	12	0	3
May 2011	13	2	2
Jun 2011	20	3	2
Jul 2011	22	5	2
Aug 2011	18	4	1
Sep 2011	24	3	2
Oct 2011	15	2	0
Nov 2011	23	7	10
Dec 2011	16	14	10
Jan 2012	11	20	10
Feb 2012	11	12	5
Mar 2012	20	25	20
Apr 2012	23	20	7
May 2012	21	25	6
Jun 2012	31	18	13
Jul 2012	19	18	15
Aug 2012	18	12	14
Sep 2012	14	13	12
Oct 2012	40	7	12
Nov 2012	25	30	11
Dec 2012	22	18	10
Jan 2013	36	24	6
Feb 2013	44	39	17
Mar 2013	35	41	15
Apr 2013	27	27	12
May 2013	20	22	8
Jun 2013	18	14	8
Jul 2013	27	11	3
Aug 2013	27	17	8
Sep 2013	27	19	6
Oct 2013	28	32	16
Nov 2013	42	38	15
Dec 2013	34	19	13
Jan 2014	22	33	10
Feb 2014	25	16	7
Mar 2014	32	23	7
Apr 2014	17	36	2
May 2014	25	41	8
Jun 2014	20	14	1
Jul 2014	26	34	3
Aug 2014	18	29	2
Sep 2014	29	31	2
Oct 2014	25	27	5
Nov 2014	21	21	3
Dec 2014	15	11	3
Jan 2015	29	14	1
Feb 2015	23	13	4
Mar 2015	24	14	3
Apr 2015	20	12	5
May 2015	20	12	7
Jun 2015	22	21	2
Jul 2015	13	13	3
Aug 2015	15	27	8
Sep 2015	29	30	2
Oct 2015	12	28	0
Nov 2015	19	7	7
Dec 2015	20	16	5
Jan 2016	28	11	5
Feb 2016	8	10	3
Mar 2016	20	8	7
Apr 2016	23	14	1
May 2016	16	9	2
Jun 2016	12	9	7
Jul 2016	26	11	11
Aug 2016	21	15	12
Sep 2016	30	20	4
Oct 2016	33	19	3
Nov 2016	26	7	1
Dec 2016	20	9	3
Jan 2017	22	17	5
Feb 2017	7	18	3
Mar 2017	2	16	5
Apr 2017	1	24	2
May 2017	1	26	4
Jun 2017	8	15	5
Jul 2017	18	18	3
Aug 2017	21	15	1
Sep 2017	25	25	3
Oct 2017	31	27	3
Nov 2017	22	18	2
Dec 2017	35	31	1
Jan 2018	47	35	8
Feb 2018	18	16	17
Mar 2018	419	419	4
Apr 2018	41	37	10
May 2018	35	27	9
Jun 2018	42	40	3
Jul 2018	40	40	5
Aug 2018	22	22	4
Sep 2018	43	43	3
Oct 2018	43	43	8
Nov 2018	53	53	10
Dec 2018	48	48	9
Jan 2019	78	76	9
Feb 2019	60	61	8
Mar 2019	96	93	8
Apr 2019	53	53	11
May 2019	53	52	10
Jun 2019	60	60	12
Jul 2019	72	65	11
Aug 2019	76	74	9
Sep 2019	57	55	3
Oct 2019	71	69	6
Nov 2019	75	75	5
Dec 2019	86	80	6
Jan 2020	109	104	3
Feb 2020	81	78	8
Mar 2020	97	95	5
Apr 2020	58	53	6
May 2020	53	53	8
Jun 2020	44	38	9
Jul 2020	52	52	6
Aug 2020	68	65	7
Sep 2020	99	91	11
Oct 2020	84	70	18
Nov 2020	100	94	7
Dec 2020	89	76	13
Jan 2021	90	82	10
Feb 2021	78	76	5
Mar 2021	95	91	14
Apr 2021	98	89	4
May 2021	90	90	5
Jun 2021	68	68	10
Jul 2021	78	78	8
Aug 2021	84	84	10
Sep 2021	91	90	10
Oct 2021	109	95	22
Nov 2021	64	56	27
Dec 2021	105	95	7
Jan 2022	97	87	15
Feb 2022	84	71	9
Mar 2022	64	63	8
Apr 2022	54	48	7
May 2022	85	70	21
Jun 2022	73	68	12
Jul 2022	45	37	8
Aug 2022	76	67	5
Sep 2022	63	56	12
Oct 2022	63	55	8
Nov 2022	63	52	11
Dec 2022	58	45	3
Jan 2023	43	34	6
Feb 2023	71	68	2
Mar 2023	45	37	6
Apr 2023	66	60	12
May 2023	48	41	11
Jun 2023	34	31	3
Jul 2023	109	95	8
Aug 2023	67	65	14
Sep 2023	60	55	9
Oct 2023	92	58	11
Nov 2023	75	59	6
Dec 2023	100	7	2
Jan 2024	77	2	2
Feb 2024	66	0	3
Mar 2024	147	5	2
Total	9235	8607	2337

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