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In the July 2000 issue of Gut, Dr Pescatore and colleagues published their experience with virtual colonoscopy and concluded that “VC does not appear to be suitable for colorectal cancer or polyp screening”.1 We commend the authors for pursuing this important topic, particularly as we anticipate virtual colonoscopy to be applied in a clinical setting. It is particularly important since their work seems to demonstrate the limitations of their technique.
(1) Bias in patient selection: most of the patients included in the study (43 out of 50) are not screening subjects but selected patients with a positive history of previous polyp/tumour, anemia, positive fecal blood test, pain, etc.
(2) Insufficient technique: patients were scanned only in supine position. Better results are achieved2– …