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Helicobacter and gastric MALT lymphoma
  1. M Stolte1,
  2. E Bayerdörffer2,
  3. A Morgner2,
  4. B Alpen3,
  5. T Wündisch3,
  6. C Thiede2,
  7. A Neubauer3
  1. 1Institut für Pathologie, Klinikum Bayreuth, 95445 Bayreuth, Germany
  2. 2Medizinische Klinik I, Universitätskliniken Dresden, 01307 Dresden, Germany
  3. 3Abtlg. Hämatologie, Onkologie, Immunologie, Philipps Universität Marburg, 35023 Marburg, Germany
  1. Correspondence to:
    Prof. Dr M Stolte, Institut für Pathologie, Klinikum Bayreuth, Preuschwitzer Str. 101, D-95445 Bayreuth, Germany;
    pathologie.klinikum{at}bnbt.de

Abstract

Helicobacter pylori infection is a pre-MALT lymphoma condition. H pylori eradication leads to complete remission in 80% of low grade stage E1 lymphomas, with a yearly recurrence rate of approximately 5%. The possibility for complete remission in high grade lymphomas needs to be investigated in prospective studies. In addition, the significance of persistent B cell monoclonality (stable disease? danger of relapse? regression of monoclonality?) needs to be investigated in follow up studies.

  • Helicobacter pylori
  • gastritis
  • MALT lymphoma
  • MALT, mucosa associated lymphatic tissue
  • PCR, polymerase chain reaction

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