rss
Gut 51:420-423 doi:10.1136/gut.51.3.420
  • Colorectal cancer

Explaining variation in familial adenomatous polyposis: relationship between genotype and phenotype and evidence for modifier genes

Table 2

Segregation analysis for within family variation in familial adenomatous polyposis

Model Gene frequency Polygenic heritability 2LogL*
*Log likelihoods are relative to the model with no familial effect.
Dominant 0.54 — 12.5
Recessive 0.15 — 11.0
Polygenic — 0.47 7.0
Mixed 0.66 0.25 20.2

This Article

  1. Abstract
  2. Full text
  3. PDF

Latest from Gut Education

Latest from Gut Education

Register for free content


Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of Gut.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.