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Review
Effect of breast milk and weaning on epithelial growth of the small intestine in humans
  1. A G Cummins,
  2. F M Thompson
  1. Bazil Hetzel Research Institute and the Department of Gastroenterology and Hepatology, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia
  1. Dr A G Cummins, Department of Gastroenterology and Hepatology, DX 465384, The Queen Elizabeth Hospital, Woodville South, SA 5011, Australia;
    adrian.cummins{at}nwahs.sa.gov.au

Abstract

Breast feeding and weaning are important physiologically significant luminal events that influence the growth of the small intestine in humans. A variety of factors including genetic preprogramming, systemic and local hormones, and permissive factors contribute and modulate intestinal growth. Here, we offer a view that integrates some of these factors, especially those relating to breast feeding and weaning.

  • breast feeding
  • growth
  • small intestine
  • weaning
  • EGF, epidermal growth factor
  • GH, growth hormone
  • KGF, keratinocyte growth factor
  • IGF-1, insulin-like growth factor 1
  • Epo, erythropoietin
  • GLP, glucagon-like polypeptide
  • TGF, transforming growth factor
  • HGF, hepatocyte growth factor

https://doi.org/10.1136/gut.51.5.748

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