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[Front cover][Table of contents PDF]

Leading article

  • Is intestinal metaplasia of the stomach reversible?

    • M M Walker
    Gut 2003;52:1 1-4 doi:10.1136/gut.52.1.1

  • Digest

    • Ian Forgacs
    Gut 2003;52:1 1 doi:10.1136/gut.52.1.1-a

Commentaries

  • s, m, L, XL . . .

    • T Wang,
    • G Triadafilopoulos
    Gut 2003;52:1 5-6 doi:10.1136/gut.52.1.5

  • HLA-DQ8 as an Ir gene in coeliac disease

    • K E A Lundin
    Gut 2003;52:1 7 doi:10.1136/gut.52.1.7

  • A rat virus visits the clinic: translating basic discoveries into clinical medicine in the 21st century

    • C R Boland,
    • A Goel
    Gut 2003;52:1 8-9 doi:10.1136/gut.52.1.8

Clinical @lert

  • Dyspepsia management in the millennium: to test and treat or not?

    • B C Delaney
    Gut 2003;52:1 10-11 doi:10.1136/gut.52.1.10

Science @lert

  • RUNX 3, apoptosis 0: a new gastric tumour suppressor

    • S F Moss
    Gut 2003;52:1 12-13 doi:10.1136/gut.52.1.12

Debate

  • Ablative mucosectomy is the procedure of choice to prevent Barrett’s cancer

    • H Barr
    Gut 2003;52:1 14-15 doi:10.1136/gut.52.1.14

  • Ablative mucosectomy is the procedure of choice to prevent Barrett’s cancer

    • R C Fitzgerald
    Gut 2003;52:1 16-17 doi:10.1136/gut.52.1.16

Oesophageal disease

  • Biopsy surveillance is still necessary in patients with Barrett’s oesophagus despite new endoscopic imaging techniques

    • K Egger,
    • M Werner,
    • A Meining,
    • R Ott,
    • H-D Allescher,
    • H Höfler,
    • M Classen,
    • T Rösch
    Gut 2003;52:1 18-23 doi:10.1136/gut.52.1.18

  • Magnification chromoendoscopy for the detection of intestinal metaplasia and dysplasia in Barrett’s oesophagus

    • P Sharma,
    • A P Weston,
    • M Topalovski,
    • R Cherian,
    • A Bhattacharyya,
    • R E Sampliner
    Gut 2003;52:1 24-27 doi:10.1136/gut.52.1.24

  • Time gated fluorescence spectroscopy in Barrett’s oesophagus

    • M-A E J Ortner,
    • B Ebert,
    • E Hein,
    • K Zumbusch,
    • D Nolte,
    • U Sukowski,
    • J Weber-Eibel,
    • B Fleige,
    • M Dietel,
    • M Stolte,
    • G Oberhuber,
    • R Porschen,
    • B Klump,
    • H Hörtnagl,
    • H Lochs,
    • H Rinneberg
    Gut 2003;52:1 28-33 doi:10.1136/gut.52.1.28

  • Endocinch therapy for gastro-oesophageal reflux disease: a one year prospective follow up

    • Z Mahmood,
    • B P McMahon,
    • Q Arfin,
    • P J Byrne,
    • J V Reynolds,
    • E M Murphy,
    • D G Weir
    Gut 2003;52:1 34-39 doi:10.1136/gut.52.1.34

Helicobacter pylori

  • Treatment of Helicobacter pylori in functional dyspepsia resistant to conventional management: a double blind randomised trial with a six month follow up

    • H R Koelz,
    • R Arnold,
    • M Stolte,
    • M Fischer,
    • A L Blum
    Gut 2003;52:1 40-46 doi:10.1136/gut.52.1.40

Small intestine

  • Avenin fails to induce a Th1 response in coeliac tissue following in vitro culture

    • C Kilmartin,
    • S Lynch,
    • M Abuzakouk,
    • H Wieser,
    • C Feighery
    Gut 2003;52:1 47-52 doi:10.1136/gut.52.1.47

  • Tachykinins potently stimulate human small bowel blood flow: a laser Doppler flowmetry study in humans

    • P T Schmidt,
    • M Lördal,
    • B Gazelius,
    • P M Hellström
    Gut 2003;52:1 53-56 doi:10.1136/gut.52.1.53

  • An immunodominant DQ8 restricted gliadin peptide activates small intestinal immune response in in vitro cultured mucosa from HLA-DQ8 positive but not HLA-DQ8 negative coeliac patients

    • G Mazzarella,
    • M Maglio,
    • F Paparo,
    • G Nardone,
    • R Stefanile,
    • L Greco,
    • Y van de Wal,
    • Y Kooy,
    • F Koning,
    • S Auricchio,
    • R Troncone
    Gut 2003;52:1 57-62 doi:10.1136/gut.52.1.57

Therapy update

  • Osteoporosis in inflammatory bowel disease

    • J Compston
    Gut 2003;52:1 63-64 doi:10.1136/gut.52.1.63

Inflammatory bowel disease

  • Increased expression of interleukin 17 in inflammatory bowel disease

    • S Fujino,
    • A Andoh,
    • S Bamba,
    • A Ogawa,
    • K Hata,
    • Y Araki,
    • T Bamba,
    • Y Fujiyama
    Gut 2003;52:1 65-70 doi:10.1136/gut.52.1.65

  • CARD4/NOD1 is not involved in inflammatory bowel disease

    • H Zouali,
    • S Lesage,
    • F Merlin,
    • J-P Cézard,
    • J-F Colombel,
    • J Belaiche,
    • S Almer,
    • C Tysk,
    • C O’Morain,
    • M Gassull,
    • S Christensen,
    • Y Finkel,
    • R Modigliani,
    • C Gower-Rousseau,
    • J Macry,
    • M Chamaillard,
    • G Thomas,
    • J-P Hugot
    Gut 2003;52:1 71-74 doi:10.1136/gut.52.1.71

  • Association between K469E allele of intercellular adhesion molecule 1 gene and inflammatory bowel disease in a Japanese population

    • J Matsuzawa,
    • K Sugimura,
    • Y Matsuda,
    • M Takazoe,
    • K Ishizuka,
    • T Mochizuki,
    • S S Seki,
    • O Yoneyama,
    • H Bannnai,
    • K Suzuki,
    • T Honma,
    • H Asakura
    Gut 2003;52:1 75-78 doi:10.1136/gut.52.1.75

  • Induction of experimental ulcerative colitis by Fusobacterium varium isolated from colonic mucosa of patients with ulcerative colitis

    • T Ohkusa,
    • I Okayasu,
    • T Ogihara,
    • K Morita,
    • M Ogawa,
    • N Sato
    Gut 2003;52:1 79-83 doi:10.1136/gut.52.1.79

  • Changes in chemical coding of myenteric neurones in ulcerative colitis

    • M Neunlist,
    • P Aubert,
    • C Toquet,
    • T Oreshkova,
    • J Barouk,
    • P A Lehur,
    • M Schemann,
    • J P Galmiche
    Gut 2003;52:1 84-90 doi:10.1136/gut.52.1.84

  • Interleukin 10 genotypes in irritable bowel syndrome: evidence for an inflammatory component?

    • W M Gonsalkorale,
    • C Perrey,
    • V Pravica,
    • P J Whorwell,
    • I V Hutchinson
    Gut 2003;52:1 91-93 doi:10.1136/gut.52.1.91

Cancer

  • Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway

    • F M Ruemmele,
    • S Schwartz,
    • E G Seidman,
    • S Dionne,
    • E Levy,
    • M J Lentze
    Gut 2003;52:1 94-100 doi:10.1136/gut.52.1.94

  • A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: strong prognostic indicator in postoperative follow up

    • B M Ryan,
    • F Lefort,
    • R McManus,
    • J Daly,
    • P W N Keeling,
    • D G Weir,
    • D Kelleher
    Gut 2003;52:1 101-108 doi:10.1136/gut.52.1.101

Biliary disease

  • Gall bladder dysmotility: a risk factor for gall stone formation in hypertriglyceridaemia and reversal on triglyceride lowering therapy by bezafibrate and fish oil

    • I J A M Jonkers,
    • A H M Smelt,
    • M Ledeboer,
    • M E Hollum,
    • I Biemond,
    • F Kuipers,
    • F Stellaard,
    • R Boverhof,
    • A E Meinders,
    • C H B W Lamers,
    • A A M Masclee
    Gut 2003;52:1 109-115 doi:10.1136/gut.52.1.109

  • Risk factors for recurrent bile duct stones after endoscopic papillotomy

    • T Ando,
    • T Tsuyuguchi,
    • T Okugawa,
    • M Saito,
    • T Ishihara,
    • T Yamaguchi,
    • H Saisho
    Gut 2003;52:1 116-121 doi:10.1136/gut.52.1.116

Liver disease

  • Different hepatitis B virus core gene mutations in children with chronic infection and hepatocellular carcinoma

    • Y-H Ni,
    • M-H Chang,
    • H-Y Hsu,
    • D-J Tsuei
    Gut 2003;52:1 122-125 doi:10.1136/gut.52.1.122

  • Impact of smoking on histological liver lesions in chronic hepatitis C

    • C Hézode,
    • I Lonjon,
    • F Roudot-Thoraval,
    • J-P Mavier,
    • J-M Pawlotsky,
    • E S Zafrani,
    • D Dhumeaux
    Gut 2003;52:1 126-129 doi:10.1136/gut.52.1.126

  • Acute propranolol administration effectively decreases portal pressure in patients with TIPS dysfunction

    • L Bellis,
    • E Moitinho,
    • J G Abraldes,
    • M Graupera,
    • J C García-Pagán,
    • J Rodés,
    • J Bosch
    Gut 2003;52:1 130-133 doi:10.1136/gut.52.1.130

  • MELD scoring system is useful for predicting prognosis in patients with liver cirrhosis and is correlated with residual liver function: a European study

    • F Botta,
    • E Giannini,
    • P Romagnoli,
    • A Fasoli,
    • F Malfatti,
    • B Chiarbonello,
    • E Testa,
    • D Risso,
    • G Colla,
    • R Testa
    Gut 2003;52:1 134-139 doi:10.1136/gut.52.1.134

Case report

  • Safe treatment of thiopurine S-methyltransferase deficient Crohn’s disease patients with azathioprine

    • B A Kaskas,
    • E Louis,
    • U Hindorf,
    • E Schaeffeler,
    • J Deflandre,
    • F Graepler,
    • K Schmiegelow,
    • M Gregor,
    • U M Zanger,
    • M Eichelbaum,
    • M Schwab
    Gut 2003;52:1 140-142 doi:10.1136/gut.52.1.140

Gut file

  • Elemental diet in the treatment of orofacial Crohn's disease

    • E A B Cameron,
    • S J Middleton
    Gut 2003;52:1 143 doi:10.1136/gut.52.1.143

Review

  • Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets

    • D W Hommes,
    • M P Peppelenbosch,
    • S J H van Deventer
    Gut 2003;52:1 144-151 doi:10.1136/gut.52.1.144

Letters

  • Living related liver transplantation: a Japanese experience and development of a checklist for donors' informed consent

    • A Akabayashi,
    • M Nishimori,
    • M Fujita,
    • B T Slingsby
    Gut 2003;52:1 152 doi:10.1136/gut.52.1.152

  • Endoscopic surveillance of premalignant gastric lesions

    • S Sebastian,
    • J Seery,
    • C O’Morain,
    • M Buckley
    Gut 2003;52:1 152-153 doi:10.1136/gut.52.1.152-a

  • Smoking and ulcer healing

    • A Duggan,
    • N Rutherford
    Gut 2003;52:1 153 doi:10.1136/gut.52.1.153

  • Oesophageal pH monitoring in Barrett's oesophagus

    • C S Neumann,
    • B T Cooper
    1. Commentator:
      • R Fass
    Gut 2003;52:1 153 doi:10.1136/gut.52.1.153-a

  • Influence of clinical factors, drug use, and food intake on the glutathione system

    • H Shirin,
    • J T Pinto,
    • S F Moss
    1. Commentator:
      • H Hoensch and
      • I Morgenstern
    Gut 2003;52:1 154 doi:10.1136/gut.52.1.154

  • Mycobacterium avium subspecies paratuberculosis as a cause of Crohn’s disease

    • D S Grimes
    Gut 2003;52:1 155 doi:10.1136/gut.52.1.155

BOOK REVIEW

  • Modern Management of Cancer of the Rectum: Edited by R A Audisio, J G Geraghty, W E Longo. Berlin: Springer-Verlag, 2001, B/W, pp 234. ISBN 1-85233-287-5.

    • R J Heald
    Gut 2003;52:1 156 doi:10.1136/gut.52.1.156

  • Management of Chronic Viral Hepatitis: Edited by S C Gordon. New York: Marcel Dekker, 2002, B/W, pp 380. ISBN 08247-0582-3

    • M Cramp
    Gut 2003;52:1 156 doi:10.1136/gut.52.1.156-a

  • Abdominal Ultrasound: M Stocksley. Greenwich Medical Media, 2001, £35.00, B/W, pp 286. ISBN 1-90015-166-9

    • N Power
    Gut 2003;52:1 156-157 doi:10.1136/gut.52.1.156-b

CORRECTION

  • CORRECTION

    Gut 2003;52:1 157 doi:10.1136/gut.52.1.157

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