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Gut 52:28-33 doi:10.1136/gut.52.1.28
  • Oesophageal disease

Time gated fluorescence spectroscopy in Barrett’s oesophagus

Table 1

Interobserver agreement: histology, p53 protein expression, and fluorescence spectroscopy

By biopsy sample By patient
Method κ agreement (%) κ agreement (%)
Pathologist A v B 0.18 52 0.15 47
Pathologist B v C 0.39 67 0.13 43
Pathologist A v C 0.67 87 0.46 76
P 53v consensus diagnosis 0.38 66 0.55 80
Fluorescence v consensus 0.40 76 0.67 86
P 53 v fluorescence 0.17 50 0.42 71
P 53 v pathologist A 0.31 68 0.72 88
P 53 v pathologist B 0.30 66 0.36 66
P 53 v pathologist C 0.35 67 0.30 64
Fluorescence v pathologist A 0.35 65 0.67 83
Fluorescence v pathologist B 0.12 36 0.35 66
Fluorescence v pathologist C 0.23 62 0.56 82

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