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Gut 52:75-78 doi:10.1136/gut.52.1.75
  • Inflammatory bowel disease

Association between K469E allele of intercellular adhesion molecule 1 gene and inflammatory bowel disease in a Japanese population

Table 4

Allelic frequencies and carriage rate of intercellular adhesion molecule 1 (ICAM-1) alleles in patients with ulcerative colitis by affected lesions

Entire colitis Left sided colitis Proctitis
Controls (n=103) (n=4) pc (n=35) pc (n=9) pc
NS, not significant compared with healthy controls.
Genotype (n)
    EE 27 9 4 3
    EK 50 47 16 3
    KK 26 28 15 3
Alleleic frequency (%)
    E469 50.5 38.7 0.0452 34.3 0.0377 50.0 NS
    K469 49.5 61.3 0.0452 65.7 0.0377 50.0 NS
Carriage rate (%)
    E469 74.8 66.6 NS 57.1 NS 66.6 NS
    K469 73.8 89.3 0.0149 88.6 NS 66.6 NS

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