Short chain fatty acids stimulate epithelial mucin 2 expression through differential effects on prostaglandin E1 and E2 production by intestinal myofibroblasts

L E M Willemsen; M A Koetsier; S J H van Deventer; E A F van Tol

doi:10.1136/gut.52.10.1442

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Inflammation and inflammatory bowel disease

Short chain fatty acids stimulate epithelial mucin 2 expression through differential effects on prostaglandin E₁ and E₂ production by intestinal myofibroblasts

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	Abstract	Full	Pdf
Sep 2003	79	105	52
Oct 2003	38	92	44
Nov 2003	31	49	30
Dec 2003	12	26	13
Jan 2004	25	37	10
Feb 2004	10	33	14
Mar 2004	23	37	15
Apr 2004	18	36	22
May 2004	35	53	14
Jun 2004	44	89	20
Jul 2004	51	54	9
Aug 2004	45	59	7
Sep 2004	30	40	8
Oct 2004	8	24	21
Nov 2004	5	40	25
Dec 2004	9	32	13
Jan 2005	8	39	17
Feb 2005	13	25	12
Mar 2005	12	31	17
Apr 2005	5	29	14
May 2005	5	25	18
Jun 2005	10	29	15
Jul 2005	4	20	16
Aug 2005	7	36	27
Sep 2005	2	29	19
Oct 2005	8	21	9
Nov 2005	6	23	11
Dec 2005	11	20	5
Jan 2006	11	21	14
Feb 2006	5	17	12
Mar 2006	10	25	8
Apr 2006	12	30	22
May 2006	6	21	15
Jun 2006	9	16	6
Jul 2006	5	22	13
Aug 2006	8	13	7
Sep 2006	4	18	4
Oct 2006	12	14	11
Nov 2006	5	12	13
Dec 2006	6	21	14
Jan 2007	4	19	9
Feb 2007	6	22	11
Mar 2007	12	29	13
Apr 2007	17	9	8
May 2007	16	11	5
Jun 2007	16	12	6
Jul 2007	10	13	6
Aug 2007	9	6	5
Sep 2007	10	3	2
Oct 2007	10	6	2
Nov 2007	7	8	9
Dec 2007	8	4	4
Jan 2008	7	11	8
Feb 2008	21	3	5
Mar 2008	23	4	5
Apr 2008	15	2	3
May 2008	12	2	4
Jun 2008	15	7	5
Jul 2008	26	2	2
Aug 2008	15	7	4
Sep 2008	31	6	4
Oct 2008	13	3	3
Nov 2008	9	2	0
Dec 2008	4	5	3
Jan 2009	9	6	6
Feb 2009	10	3	4
Mar 2009	14	2	2
Apr 2009	15	3	4
May 2009	11	2	3
Jun 2009	16	2	5
Jul 2009	10	4	4
Aug 2009	10	5	1
Sep 2009	14	7	3
Oct 2009	19	5	4
Nov 2009	7	8	7
Dec 2009	10	0	6
Jan 2010	9	1	3
Feb 2010	12	2	2
Mar 2010	10	7	3
Apr 2010	13	6	8
May 2010	13	5	4
Jun 2010	15	1	4
Jul 2010	24	1	6
Aug 2010	16	3	5
Sep 2010	12	10	4
Oct 2010	16	6	2
Nov 2010	16	4	1
Dec 2010	8	13	3
Jan 2011	14	4	5
Feb 2011	19	4	3
Mar 2011	6	4	5
Apr 2011	12	4	1
May 2011	18	4	7
Jun 2011	10	4	2
Jul 2011	12	5	3
Aug 2011	18	8	5
Sep 2011	20	8	4
Oct 2011	24	3	6
Nov 2011	15	15	12
Dec 2011	19	17	12
Jan 2012	8	24	7
Feb 2012	16	31	10
Mar 2012	18	11	9
Apr 2012	23	16	8
May 2012	12	27	10
Jun 2012	22	34	16
Jul 2012	15	30	12
Aug 2012	13	29	14
Sep 2012	15	25	9
Oct 2012	19	24	12
Nov 2012	17	18	16
Dec 2012	28	60	17
Jan 2013	30	53	19
Feb 2013	19	22	9
Mar 2013	28	29	22
Apr 2013	18	39	12
May 2013	18	24	12
Jun 2013	6	12	3
Jul 2013	15	41	15
Aug 2013	10	53	12
Sep 2013	20	56	13
Oct 2013	13	53	13
Nov 2013	29	37	16
Dec 2013	16	65	19
Jan 2014	21	46	9
Feb 2014	16	34	9
Mar 2014	17	21	3
Apr 2014	6	29	11
May 2014	14	43	7
Jun 2014	24	32	5
Jul 2014	23	30	4
Aug 2014	33	27	13
Sep 2014	15	28	4
Oct 2014	13	35	8
Nov 2014	15	39	8
Dec 2014	34	56	5
Jan 2015	19	50	8
Feb 2015	19	56	14
Mar 2015	28	37	9
Apr 2015	23	27	10
May 2015	5	29	9
Jun 2015	4	21	9
Jul 2015	16	26	5
Aug 2015	16	24	10
Sep 2015	26	30	4
Oct 2015	17	13	3
Nov 2015	17	27	10
Dec 2015	10	27	4
Jan 2016	14	24	11
Feb 2016	20	17	11
Mar 2016	12	21	14
Apr 2016	17	30	10
May 2016	18	21	12
Jun 2016	19	18	7
Jul 2016	18	11	4
Aug 2016	17	20	9
Sep 2016	16	43	19
Oct 2016	22	24	10
Nov 2016	19	48	8
Dec 2016	14	22	4
Jan 2017	21	29	13
Feb 2017	15	26	10
Mar 2017	0	34	8
Apr 2017	0	42	4
May 2017	0	33	6
Jun 2017	5	23	4
Jul 2017	34	34	12
Aug 2017	49	49	15
Sep 2017	25	25	12
Oct 2017	35	35	3
Nov 2017	96	96	11
Dec 2017	180	180	6
Jan 2018	131	131	8
Feb 2018	170	152	7
Mar 2018	41	39	15
Apr 2018	99	99	15
May 2018	158	158	10
Jun 2018	68	68	5
Jul 2018	43	43	14
Aug 2018	51	51	13
Sep 2018	113	113	10
Oct 2018	100	100	13
Nov 2018	129	129	12
Dec 2018	109	109	11
Jan 2019	68	67	7
Feb 2019	62	62	5
Mar 2019	43	42	16
Apr 2019	49	40	23
May 2019	52	43	29
Jun 2019	65	56	25
Jul 2019	33	29	9
Aug 2019	52	43	29
Sep 2019	54	46	18
Oct 2019	66	56	18
Nov 2019	45	42	19
Dec 2019	41	34	16
Jan 2020	41	34	14
Feb 2020	38	25	26
Mar 2020	43	31	27
Apr 2020	47	39	32
May 2020	42	33	17
Jun 2020	89	86	20
Jul 2020	86	81	20
Aug 2020	40	34	33
Sep 2020	49	36	22
Oct 2020	48	38	18
Nov 2020	41	35	17
Dec 2020	48	39	34
Jan 2021	30	25	26
Feb 2021	44	30	32
Mar 2021	47	42	46
Apr 2021	36	33	18
May 2021	66	56	26
Jun 2021	46	37	36
Jul 2021	34	28	29
Aug 2021	43	35	30
Sep 2021	44	40	27
Oct 2021	69	63	58
Nov 2021	38	32	28
Dec 2021	37	33	22
Jan 2022	49	46	30
Feb 2022	66	59	30
Mar 2022	68	54	40
Apr 2022	70	58	24
May 2022	98	65	54
Jun 2022	98	85	39
Jul 2022	67	58	39
Aug 2022	111	113	21
Sep 2022	73	61	49
Oct 2022	75	69	32
Nov 2022	115	112	29
Dec 2022	97	91	36
Jan 2023	91	72	36
Feb 2023	86	79	29
Mar 2023	87	74	38
Apr 2023	65	43	31
May 2023	63	57	33
Jun 2023	50	47	34
Jul 2023	53	47	25
Aug 2023	90	74	29
Sep 2023	60	51	23
Oct 2023	199	190	28
Nov 2023	369	349	35
Dec 2023	231	14	10
Jan 2024	262	10	4
Feb 2024	304	6	4
Mar 2024	141	7	8
Total	9110	8958	3425

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