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Gut 2003;52:1505-1510 doi:10.1136/gut.52.10.1505
  • Liver

Evidence for altered vascular responses to exogenous endothelin-1 in patients with advanced cirrhosis with restoration of the normal vasoconstrictor response following successful liver transplantation

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Figure 2
Figure 2

(A) Forearm blood flow (FBF) response to an intra-arterial infusion of the ETA receptor antagonist, BQ123, over 60 minutes in patients with advanced cirrhosis (before transplantation) and in healthy control subjects. Flow is expressed as percentage change from baseline flow. The blood flow response in patients with cirrhosis was the same as that in controls (p = 0.99, two way ANOVA). (B) Mean area under the curve for each group is shown. There was no significant difference in the degree of overall vasodilatation observed between the cirrhosis and control groups.

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