Table 1
Lynch cancer family syndrome II (LCFS2) associated vascular networks (LCFS2−) display significantly increased complexity, together with increased destructured randomness, and decreased vessel tortuosity compared with control (LCFS2, group C) networks. LCFS2 gene mutation carriers (group A) show higher complexity at smaller scales and a more marked destructured randomness than non-carriers (group B)
| Vascular network variable | LCFS2+ | LCFS2− controls (group C, n = 30) | F2,41 values | p Value | Significant pairwise differences | |
|---|---|---|---|---|---|---|
| Gene carriers (group A, n = 5) | Non-carriers (group B, n = 9) | |||||
| Data are means (SD). | ||||||
| p values refer to one way ANOVA results. | ||||||
| D (1–46) | 1.84 (0.07) | 1.82 (0.02) | 1.68 (0.08) | 17.97 | 2.5×10−5 | A v C; B v C |
| D (1–15) | 1.59 (0.12) | 1.47 (0.07) | 1.20 (0.09) | 71.83 | <10−6 | A v B; A v C; B v C |
| Dmin | 0.99 (0.02) | 1.03 (0.04) | 1.07 (0.04) | 9.07 | 0.00054 | A v C; B v C |
| L-Z | 0.85 (0.106) | 0.73 (0.05) | 0.56 (0.03) | 20.78 | 6×10−6 | A v B; A v C; B v C |
