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Fetal “cardiac mucosa” is not adult cardiac mucosa
  1. P T Chandrasoma
  1. Professor of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, USA; ptchandr@usc.edu

https://doi.org/10.1136/gut.52.12.1798

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    De Hertogh et al’s autopsy study of the fetal gastro-oesophageal region provides valuable insight into the development of foregut epithelium in the 13–24 week gestational period (Gut 2003;52:791–6). Coincidentally, two other studies appeared on the same subject in April 2003.1,2 These studies were stimulated by our hypothesis that cardiac mucosa does not exist as a normal structure in humans.3,4

    Three columnar epithelial types are reported between squamous epithelium and parietal cell containing gastric mucosa in De Hertogh’s study (Gut 2003;52:791–6). These are called “primitive oesophageal mucosa”, “primitive stomach mucosa”, and “cardiac mucosa”. Careful anatomical correlation place all of these mucosae in the oesophagus, proximal to the gastro-oesophageal junction. “Primitive oesophageal mucosa” is a ciliated epithelium …

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