Table 1
Rat body and liver weights at various stages of chronic liver disease
| Group | n | Body weight (g) | Liver weight (g) |
|---|---|---|---|
| Values are means (SEM). | |||
| *p<0.05 versus stages 0 and 1; †p<0.05 versus stage 1; ‡ p<0.05 versus baseline; § p<0.05 versus baseline and age matched controls. | |||
| Thioacetamide series | |||
| Stage 0 | 9 | 341 (15) | 14.8 (0.9) |
| Stage 1 | 4 | 270 (9.0) | 11.1 (0.6) |
| Stage 2 | 4 | 410 (15)* | 15.0 (1.6) |
| Stage 3 | 7 | 423 (15)* | 19.1 (1.5)† |
| Stage 4 | 9 | 415 (15)* | 19.7 (1.6)† |
| Carbon tetrachloride series | |||
| Stage 1 | 6 | 433 (12) | 11 (0.5) |
| Stage 4 | 10 | 413 (11) | 13 (1.0) |
| Common bile duct ligation series | |||
| Baseline | 8 | 283 (7.0) | — |
| Cholestasis | |||
| 11 days | 9 | 295 (7.0) | — |
| 26 days | 9 | 344 (10)‡ | — |
| 46 days | 7 | 376 (24)§ | 20.0 (2.1) |
| Age matched controls | 4 | 461 (12) | 14.1 (0.9) |
