Table 9
Concentrations (mM) of hepatic phosphorylated metabolites in control rats and rats with chronic cholestatic liver disease following common bile duct ligation
| Time | PME | Pi | PDE | ATP |
|---|---|---|---|---|
| Values are means (SEM). | ||||
| PME, phosphomonoesters; Pi, inorganic phosphate; PDE, phosphodiesters; ATP, adenosine triphosphate. | ||||
| *p<0.05 versus baseline, aged matched controls, 12 day, and 27 day cholestatic rats. | ||||
| Baseline | 3.05 (0.24) | 1.64 (0.11) | 0.94 (0.15) | 3.13 (0.22) |
| 12 days | 3.21 (0.19) | 1.56 (0.10) | 1.01 (0.07) | 2.69 (0.22) |
| 27 days | 3.20 (0.28) | 1.72 (0.16) | 0.98 (0.09) | 2.60 (0.30) |
| 46 days | 2.64 (0.30) | 1.43 (0.17) | 0.97 (0.19) | 1.66 (0.13)* |
| Age matched controls | 3.04 (0.13) | 1.30 (0.03) | 1.49 (0.37) | 3.28 (0.34) |
