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Gut 2004;53:1391-1393 doi:10.1136/gut.2004.044990
  • Leading article

Food allergy in irritable bowel syndrome: new facts and old fallacies

  1. E Isolauri1,
  2. S Rautava1,
  3. M Kalliomäki2
  1. 1Department of Paediatrics, University of Turku and Turku University Central Hospital, Finland
  2. 2Massachusetts General Hospital East, Combined Program in Pediatric Gastroenterology and Nutrition, Charlestown, Massachusetts, USA
  1. Correspondence to:
    Dr E Isolauri
    Department of Paediatrics, Turku University Central Hospital, 20520 Turku, Finland; erika.isolauriutu.fi
  • Received 10 June 2004
  • Accepted 19 June 2004

Abstract

The notion of food allergy in irritable bowel syndrome (IBS) is not new. However, recent evidence suggests significant reduction in IBS symptom severity in patients on elimination diets, provided that dietary elimination is based on foods against which the individual had raised IgG antibodies. These findings should encourage studies dissecting the mechanisms responsible for IgG production against dietary antigens and their putative role in IBS

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