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Letter
Risk of duodenal cancer in patients with familial adenomatous polyposis
  1. G Biasco,
  2. M A Pantaleo,
  3. G Di Febo,
  4. C Calabrese,
  5. G Brandi
  1. University of Bologna, Bologna, Italy
  1. Correspondence to:
    Dr G Biasco
    Department of Ematology and Medical Oncology, University of Bologna, Via Massarenti 9, Bologna 40138, Italy; gbiascomed.unibo.it

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    Bülow et al published results of a prospective multicentre study on analysis of the natural history of duodenal adenomas in familial adenomatous polyposis (FAP) (Gut 2004;53:381–6).

    A total of 368 patients were examined over a mean period of 7.6 years (range 0.5–10.4). They showed significant progression of Spigelman stage over time (p<0.0001). At the end of the study, the incidence of Spigelman stage IV was 7.0%. These results are lower than those …

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