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Primary antiphospholipid syndrome as a new cause of autoimmune pancreatitis
  1. H L Spencer
  1. Correspondence to:
    Dr H L Spencer
    Sheffield Teaching Hospitals, Herries Rd, Sheffield, UK; happyhalcheerful.com

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I read with interest the article by Kamisawa et al regarding the aetiology of autoimmune pancreatitis (

). The cause of a significant proportion of cases of acute pancreatitis remains uncertain. I would like to describe a case of acute pancreatitis associated with antiphospholipid syndrome to highlight another potentially important cause of autoimmune pancreatitis which I believe has not been previously described.

Case report

A 30 year old woman was admitted twice in the space of three months with acute pancreatitis. She had a past medical history of anxiety and occasional migraines, for which she took alprazolam and propranolol, respectively. She had suffered two miscarriages and had one healthy child. She drank 3 units of alcohol per day. She was otherwise well and had no history of musculoskeletal problems.

On both occasions her amylase level was significantly elevated (787 and 364, respectively (normal range 30–154)). Ultrasound and computed tomography of her abdomen were carried out each time and demonstrated a …

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