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Letter
Late development of cholangiocarcinoma after hepaticojejunostomy due to ampullary carcinoma
  1. D Padilla,
  2. T Cubo,
  3. R Pardo,
  4. J M Molina,
  5. J Hernández
  1. Department of Surgery, Complejo Hospitalario, 13005 Ciudad Real, Spain
  1. Correspondence to:
    Dr D Padilla;
    maynonaterra.es

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    We read with great interest the article by

    Bettschart et al (Gut2002;50:128–9)
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    which found an increase in cholangiocarcinoma incidence after biliary-enteric drainage for benign disease.

    In their hypothesis, changes in biliary epithelium were induced by toxic carcinogenesis due to reflux of intestinal contents and bile stasis. However, this chronic irritation and carcinogenesis of the biliary mucosa after biliary-enteric anastomosis has not been reported after surgery for malignant disease. We present a case of a …

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