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Leading article

  • When saliva meets acid: chemical warfare at the oesophagogastric junction

    • K E L McColl
    Gut 2005;54:1 1-3 doi:10.1136/gut.2004.047126

Digest

Commentaries

  • Immune regulation and colitis: suppression of acute inflammation allows the development of chronic inflammatory bowel disease

    • B Eksteen,
    • L S K Walker,
    • D H Adams
    Gut 2005;54:1 4-6 doi:10.1136/gut.2004.047084

  • Will worms really cure Crohn’s disease?

    • G L Radford-Smith
    Gut 2005;54:1 6-8 doi:10.1136/gut.2004.044917

  • Resistance to lamivudine therapy: is there more than meets the eye?

    • G Dusheiko,
    • A Bertoletti
    Gut 2005;54:1 9-10 doi:10.1136/gut.2004.047548

Gastro-oesophageal reflux

  • Dietary intake and the risk of gastro-oesophageal reflux disease: a cross sectional study in volunteers

    • H B El-Serag,
    • J A Satia,
    • L Rabeneck
    Gut 2005;54:1 11-17 doi:10.1136/gut.2004.040337

Stomach

  • Stomach regulates energy balance via acylated ghrelin and desacyl ghrelin

    • A Asakawa,
    • A Inui,
    • M Fujimiya,
    • R Sakamaki,
    • N Shinfuku,
    • Y Ueta,
    • M M Meguid,
    • M Kasuga
    Gut 2005;54:1 18-24 doi:10.1136/gut.2004.038737

  • Human peripheral and gastric lymphocyte responses to Helicobacter pylori NapA and AphC differ in infected and uninfected individuals

    • H J Windle,
    • Y S Ang,
    • V A Morales,
    • R McManus,
    • D Kelleher
    Gut 2005;54:1 25-32 doi:10.1136/gut.2003.025494

  • Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma

    • H Mutoh,
    • S Sakurai,
    • K Satoh,
    • H Osawa,
    • T Tomiyama,
    • H Kita,
    • T Yoshida,
    • K Tamada,
    • H Yamamoto,
    • N Isoda,
    • K Ido,
    • K Sugano
    Gut 2005;54:1 33-39 doi:10.1136/gut.2004.042770

Gastrointestinal cancer

  • Predictive value of alarm features in a rapid access upper gastrointestinal cancer service

    • N Kapoor,
    • A Bassi,
    • R Sturgess,
    • K Bodger
    Gut 2005;54:1 40-45 doi:10.1136/gut.2004.039438

Coeliac disease

  • Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa

    • V M Salvati,
    • G Mazzarella,
    • C Gianfrani,
    • M K Levings,
    • R Stefanile,
    • B De Giulio,
    • G Iaquinto,
    • N Giardullo,
    • S Auricchio,
    • M G Roncarolo,
    • R Troncone
    Gut 2005;54:1 46-53 doi:10.1136/gut.2003.023150

  • Malignant lymphomas in coeliac disease: evidence of increased risks for lymphoma types other than enteropathy-type T cell lymphoma

    • K E Smedby,
    • M Åkerman,
    • H Hildebrand,
    • B Glimelius,
    • A Ekbom,
    • J Askling
    Gut 2005;54:1 54-59 doi:10.1136/gut.2003.032094

Inflammatory bowel disease

  • CD4+ T cell mediated intestinal immunity: chronic inflammation versus immune regulation

    • A M Westendorf,
    • M Templin,
    • R Geffers,
    • S Deppenmeier,
    • A D Gruber,
    • M Probst-Kepper,
    • W Hansen,
    • R S Liblau,
    • F Gunzer,
    • D Bruder,
    • J Buer
    Gut 2005;54:1 60-69 doi:10.1136/gut.2003.037663

  • CD40 antisense oligonucleotide inhibition of trinitrobenzene sulphonic acid induced rat colitis

    • D Gao,
    • A H Wagner,
    • S Fankhaenel,
    • T Stojanovic,
    • S Schweyer,
    • S Panzner,
    • M Hecker
    Gut 2005;54:1 70-77 doi:10.1136/gut.2003.029587

  • CD4+CD45RBHi T cell transfer induced colitis in mice is accompanied by osteopenia which is treatable with recombinant human osteoprotegerin

    • F R Byrne,
    • S Morony,
    • K Warmington,
    • Z Geng,
    • H L Brown,
    • S A Flores,
    • M Fiorino,
    • S L Yin,
    • D Hill,
    • V Porkess,
    • D Duryea,
    • J K Pretorius,
    • S Adamu,
    • R Manuokian,
    • D M Danilenko,
    • I Sarosi,
    • D L Lacey,
    • P J Kostenuik,
    • G Senaldi
    Gut 2005;54:1 78-86 doi:10.1136/gut.2003.035113

  • Trichuris suis therapy in Crohn’s disease

    • R W Summers,
    • D E Elliott,
    • J F Urban, Jr,
    • R Thompson,
    • J V Weinstock
    Gut 2005;54:1 87-90 doi:10.1136/gut.2004.041749

  • PSC-IBD: a unique form of inflammatory bowel disease associated with primary sclerosing cholangitis

    • E V Loftus , Jr,
    • G C Harewood,
    • C G Loftus,
    • W J Tremaine,
    • W S Harmsen,
    • A R Zinsmeister,
    • D A Jewell,
    • W J Sandborn
    Gut 2005;54:1 91-96 doi:10.1136/gut.2004.046615

Miscellanea

  • An unusual cause of diarrhoea in a patient with colitis

    • M Karmo,
    • J Goh,
    • R Boulton,
    • D S A Sanders
    Gut 2005;54:1 77 doi:10.1136/gut.2004.043240

  • Vomiting in the recently anticoagulated patient

    • R A Cahill,
    • S Siddique,
    • J O’Connor
    Gut 2005;54:1 90 doi:10.1136/gut.2004.040071

  • EDITOR’S QUIZ: GI SNAPSHOT

    Gut 2005;54:1 96

  • EDITOR’S QUIZ: GI SNAPSHOT

    Gut 2005;54:1 102

  • Oesophageal ulceration: more than meets the naked eye?

    • J W Cash,
    • C McConville,
    • D O’Rourke,
    • T Harding
    Gut 2005;54:1 127 doi:10.1136/gut.2003.033308

  • EDITOR’S QUIZ: GI SNAPSHOT

    Gut 2005;54:1 133

  • Chronic diarrhoea after allogenic bone marrow transplantation

    • B Radu,
    • M Allez,
    • J-M Gornet,
    • M Lemann,
    • G Socie,
    • E Gluckman,
    • A-M Zagdanski
    Gut 2005;54:1 161 doi:10.1136/gut.2004.041335

  • EDITOR’S QUIZ: GI SNAPSHOTS

    Gut 2005;54:1 174

Colorectal cancer

  • Cost effectiveness of a new strategy to identify HNPCC patients

    • W Kievit,
    • J H F M de Bruin,
    • E M M Adang,
    • J L Severens,
    • J H Kleibeuker,
    • R H Sijmons,
    • T J Ruers,
    • F M Nagengast,
    • H F A Vasen,
    • J H J M van Krieken,
    • M J L Ligtenberg,
    • N Hoogerbrugge
    Gut 2005;54:1 97-102 doi:10.1136/gut.2004.039123

  • Low level microsatellite instability may be associated with reduced cancer specific survival in sporadic stage C colorectal carcinoma

    • C M Wright,
    • O F Dent,
    • R C Newland,
    • M Barker,
    • P H Chapuis,
    • E L Bokey,
    • J P Young,
    • B A Leggett,
    • J R Jass,
    • G A Macdonald
    Gut 2005;54:1 103-108 doi:10.1136/gut.2003.034579

Pancreatic cancer

  • Dominant negative inhibitors of signalling through the phosphoinositol 3-kinase pathway for gene therapy of pancreatic cancer

    • V Stoll,
    • V Calleja,
    • G Vassaux,
    • J Downward,
    • N R Lemoine
    Gut 2005;54:1 109-116 doi:10.1136/gut.2004.046706

Liver

  • Adiponectin and its receptors in non-alcoholic steatohepatitis

    • S Kaser,
    • A Moschen,
    • A Cayon,
    • A Kaser,
    • J Crespo,
    • F Pons-Romero,
    • C F Ebenbichler,
    • J R Patsch,
    • H Tilg
    Gut 2005;54:1 117-121 doi:10.1136/gut.2003.037010

  • Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study

    • E L Thomas,
    • G Hamilton,
    • N Patel,
    • R O’Dwyer,
    • C J Doré,
    • R D Goldin,
    • J D Bell,
    • S D Taylor-Robinson
    Gut 2005;54:1 122-127 doi:10.1136/gut.2003.036566

  • Hepatic vein transit times using a microbubble agent can predict disease severity non-invasively in patients with hepatitis C

    • A K P Lim,
    • S D Taylor-Robinson,
    • N Patel,
    • R J Eckersley,
    • R D Goldin,
    • G Hamilton,
    • G R Foster,
    • H C Thomas,
    • D O Cosgrove,
    • M J K Blomley
    Gut 2005;54:1 128-133 doi:10.1136/gut.2003.030965

  • Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury

    • S Sanz,
    • J B Pucilowska,
    • S Liu,
    • C M Rodríguez-Ortigosa,
    • P K Lund,
    • D A Brenner,
    • C R Fuller,
    • J G Simmons,
    • A Pardo,
    • M-L Martínez-Chantar,
    • J A Fagin,
    • J Prieto
    Gut 2005;54:1 134-141 doi:10.1136/gut.2003.024505

  • Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis

    • L Xu,
    • A Y Hui,
    • E Albanis,
    • M J Arthur,
    • S M O’Byrne,
    • W S Blaner,
    • P Mukherjee,
    • S L Friedman,
    • F J Eng
    Gut 2005;54:1 142-151 doi:10.1136/gut.2004.042127

  • High frequency of functional anti-YMDD and -mutant cytotoxic T lymphocytes after in vitro expansion correlates with successful response to lamivudine therapy for chronic hepatitis B

    • C-L Lin,
    • S-L Tsai,
    • T-H Lee,
    • R-N Chien,
    • S-K Liao,
    • Y-F Liaw
    Gut 2005;54:1 152-161 doi:10.1136/gut.2003.032920

Recent advances in clinical practice

  • Genotypes and phenotypes in Crohn’s disease: do they help in clinical management?

    • C Gasche,
    • P Grundtner
    Gut 2005;54:1 162-167 doi:10.1136/gut.2003.035600

JournalScan

Letters

  • An alternative to prophylactic colectomy for colon cancer prevention in HNPCC syndrome

    • S Olschwang,
    • P Laurent-Puig,
    • F Eisinger,
    • B Millat
    Gut 2005;54:1 169 doi:10.1136/gut.2004.047613

  • Serum pro-hepcidin: measuring active hepcidin or a non-functional precursor?

    • M J Brookes,
    • N K Sharma,
    • C Tselepis,
    • T H Iqbal
    Gut 2005;54:1 169-170 doi:10.1136/gut.2004.047639

  • Use of oesophageal dilatation in clinical practice

    • S J O Veldhuyzen van Zanten
    Gut 2005;54:1 170 doi:10.1136/gut.2004.047605

  • Variant Creutzfeldt-Jakob disease: update

    • M G Bramble,
    • J Ironside
    Gut 2005;54:1 170 doi:10.1136/gut.2004.048231

  • Is mesalazine really safe for use in breastfeeding mothers?

    • D A Silverman,
    • J Ford,
    • I Shaw,
    • C S J Probert
    Gut 2005;54:1 170-171 doi:10.1136/gut.2004.048058

  • Duodenal adenoma and cancer in FAP

    • A R Latchford,
    • R K S Phillips
    Gut 2005;54:1 171 doi:10.1136/gut.2004.049858

  • Treatment of recurrent gastrointestinal haemorrhage in a patient with von Willebrand’s disease with octreotide LAR and propranolol

    • N Krikis,
    • K Tziomalos,
    • V Perifanis,
    • S Vakalopoulou,
    • A Karagiannis,
    • V Garipidou,
    • F Harsoulis
    Gut 2005;54:1 171-172 doi:10.1136/gut.2004.049031

  • Antiviral treatment initiation costs in chronic hepatitis C

    • U Siebert,
    • J Wasem,
    • S Rossol,
    • G Sroczynski,
    • P Aidelsburger,
    • U Ravens-Sieberer,
    • B M Kurth,
    • M P Manns,
    • J G McHutchison,
    • J B Wong
    Gut 2005;54:1 172-173

  • Adherence to BSG adenoma surveillance guidelines will reduce colonoscopic workload

    • R C Thomas,
    • C Selinger,
    • M D Rutter
    Gut 2005;54:1 173 doi:10.1136/gut.2004.049924

CORRECTION

  • CORRECTION

    Gut 2005;54:1 173 doi:10.1136/gut.2003.026963corr1

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