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Plexiform neurofibroma mimicking a pancreatic cystic tumour
  1. A Handra-Luca1,
  2. D Vidaud2,
  3. M-P Vullierme3,
  4. N Colnot4,
  5. D Henin5,
  6. P Ruszniewski6,
  7. P Bedossa7,
  8. A Couvelard7
  1. 1Department of Pathology, Jean Verdier and Beaujon Hospitals, Assistance Publique-Hôpitaux de Paris, France
  2. 2Department of Biochemistry, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, France
  3. 3Department of Radiology, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, France
  4. 4Department of Pathology, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, France
  5. 5Department of Pathology, Bichat-Claude Bernard Hospital, Assistance Publique-Hôpitaux Paris, France
  6. 6Department of Gastroenterology, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, France
  7. 7Department of Pathology, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, France
  1. Correspondence to:
    Dr A Handra-Luca
    MD PhD, Service d’Anatomie Pathologique, Assistance Publique-Hopitaux Paris, Hôpital Jean Verdier, Avenue du 14 Juillet, 93143 Bondy, France; adriana.handra-lucajvr.ap-hop-paris.fr

https://doi.org/10.1136/gut.2005.074609

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    Pancreatic neurogenic tumours are extremely rare.1–3 Among benign neurogenic tumours, schwannoma is more frequently encountered.2,3 We report here the case of a plexiform neurofibroma, a type of neurogenic tumour in the pancreas, to our knowledge previously unreported.

    History

    A 44 year old Caucasian female patient was hospitalised for epigastric and right abdominal pain lasting for seven months. Abdominal ultrasound and computed tomography showed a cystic lesion located in the superior and anterior part of the pancreatic isthmus, with a maximal diameter of 3.5 cm (fig 1A, B). T2 magnetic resonance imaging demonstrated a trilobar cystic lesion with strong hyperintensity (fig 1B); no communication with the main pancreatic duct was noted at magnetic resonance cholangiopancreatography (fig 1C). Endoscopic ultrasound (EUS) showed a cystic lesion containing heterogeneous fluid (fig 1D). EUS guided fine needle aspiration provided mucoid fluid with no epithelial cells. Fluid pancreatic enzyme concentrations were 423 and 1204 U/l for amylase and lipase, respectively, while CEA, CA 19.9, and …

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