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Leading article

  • Brain imaging and its implications for studying centrally targeted treatments in irritable bowel syndrome: a primer for gastroenterologists

    • D A Drossman
    Gut 2005;54:5 569-573 doi:10.1136/gut.2004.058446

Digest

Commentaries

  • Clinical epidemiology—how important now?

    • V Binder
    Gut 2005;54:5 574-575 doi:10.1136/gut.2004.055111

  • Increased deoxycholic acid absorption and gall stones in acromegalic patients treated with octreotide: more evidence for a connection between slow transit constipation and gall stones

    • A F Hofmann
    Gut 2005;54:5 575-578 doi:10.1136/gut.2004.048074

  • Reversal of DNA hypomethylation by folic acid supplements: possible role in colorectal cancer prevention

    • J C Mathers
    Gut 2005;54:5 579-581 doi:10.1136/gut.2004.059881

  • Autoimmune pancreatitis—also a Western disease

    • R Sutton
    Gut 2005;54:5 581-583 doi:10.1136/gut.2004.058438

Helicobacter

  • Roles of virD4 and cagG genes in the cag pathogenicity island of Helicobacter pylori using a Mongolian gerbil model

    • H Saito,
    • Y Yamaoka,
    • S Ishizone,
    • F Maruta,
    • A Sugiyama,
    • D Y Graham,
    • K Yamauchi,
    • H Ota,
    • S Miyagawa
    Gut 2005;54:5 584-590 doi:10.1136/gut.2004.058982

Gastric cancer

  • Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts

    • Y Min,
    • Y Adachi,
    • H Yamamoto,
    • A Imsumran,
    • Y Arimura,
    • T Endo,
    • Y Hinoda,
    • C-T Lee,
    • S Nadaf,
    • D P Carbone,
    • K Imai
    Gut 2005;54:5 591-600 doi:10.1136/gut.2004.048926

Irritable bowel syndrome

  • Amitriptyline reduces rectal pain related activation of the anterior cingulate cortex in patients with irritable bowel syndrome

    • V Morgan,
    • D Pickens,
    • S Gautam,
    • R Kessler,
    • H Mertz
    Gut 2005;54:5 601-607 doi:10.1136/gut.2004.047423

Gut motility

  • Role of cyclooxygenases 1 and 2 in the modulation of neuromuscular functions in the distal colon of humans and mice

    • M Fornai,
    • C Blandizzi,
    • R Colucci,
    • L Antonioli,
    • N Bernardini,
    • C Segnani,
    • B Baragatti,
    • S Barogi,
    • P Berti,
    • R Spisni,
    • M Del Tacca
    Gut 2005;54:5 608-616 doi:10.1136/gut.2004.053322

Miscellanea

  • An unusual case of terminal ileal stricture

    • D R Gaya,
    • A J Morris,
    • J J Going
    Gut 2005;54:5 616 doi:10.1136/gut.2004.048769

  • How to evaluate a gastric submucosal tumour in a patient with haematemesis?

    • J Boujaoude,
    • B Abboud,
    • G Abadjian
    Gut 2005;54:5 629 doi:10.1136/gut.2004.054874

  • EDITOR’S QUIZ: GI SNAPSHOT

    Gut 2005;54:5 653

  • Liver failure after delivery

    • C J M de Groot,
    • G M van Goor,
    • M F Stolk,
    • H J Metselaar,
    • H L A Janssen,
    • G Kazemier,
    • P E Zondervan,
    • I R Wanless
    Gut 2005;54:5 672 Published Online First: 14 April 2005 doi:10.1136/gut.2004.045252

  • EDITOR’S QUIZ: GI SNAPSHOT

    Gut 2005;54:5 697

  • EDITOR’S QUIZ: GI SNAPSHOT

    Gut 2005;54:5 709

Inflammatory bowel disease

  • Risk of haematopoietic cancer in patients with inflammatory bowel disease

    • J Askling,
    • L Brandt,
    • A Lapidus,
    • P Karlén,
    • M Björkholm,
    • R Löfberg,
    • A Ekbom
    Gut 2005;54:5 617-622 doi:10.1136/gut.2004.051771

  • Activation of RegIIIβ/γ and interferon γ expression in the intestinal tract of SCID mice: an innate response to bacterial colonisation of the gut

    • S A Keilbaugh,
    • M E Shin,
    • R F Banchereau,
    • L D McVay,
    • N Boyko,
    • D Artis,
    • J J Cebra,
    • G D Wu
    Gut 2005;54:5 623-629 doi:10.1136/gut.2004.056028

Colon

  • Octreotide induced prolongation of colonic transit increases faecal anaerobic bacteria, bile acid metabolising enzymes, and serum deoxycholic acid in patients with acromegaly

    • L A Thomas,
    • M J Veysey,
    • G M Murphy,
    • D Russell-Jones,
    • G L French,
    • J A H Wass,
    • R H Dowling
    Gut 2005;54:5 630-635 doi:10.1136/gut.2003.028431

Colorectal cancer

  • Association between family history and mismatch repair in colorectal cancer

    • R P Coggins,
    • L Cawkwell,
    • S M Bell,
    • G P Crockford,
    • P Quirke,
    • P J Finan,
    • D T Bishop
    Gut 2005;54:5 636-642 doi:10.1136/gut.2003.017517

  • The C/C−13910 genotype of adult-type hypolactasia is associated with an increased risk of colorectal cancer in the Finnish population

    • H Rasinperä,
    • C Forsblom,
    • N S Enattah,
    • P Halonen,
    • K Salo,
    • M Victorzon,
    • J-P Mecklin,
    • H Järvinen,
    • S Enholm,
    • G Sellick,
    • H Alazzouzi,
    • R Houlston,
    • J Robinson,
    • P-H Groop,
    • I Tomlinson,
    • S Schwartz, Jr,
    • L A Aaltonen,
    • I Järvelä
    Gut 2005;54:5 643-647 doi:10.1136/gut.2004.055939

  • Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma

    • M Pufulete,
    • R Al-Ghnaniem,
    • A Khushal,
    • P Appleby,
    • N Harris,
    • S Gout,
    • P W Emery,
    • T A B Sanders
    Gut 2005;54:5 648-653 doi:10.1136/gut.2004.054718

  • Increased microvascular blood content is an early event in colon carcinogenesis

    • R K Wali,
    • H K Roy,
    • Y L Kim,
    • Y Liu,
    • J L Koetsier,
    • D P Kunte,
    • M J Goldberg,
    • V Turzhitsky,
    • V Backman
    Gut 2005;54:5 654-660 doi:10.1136/gut.2004.056010

  • Impaired CD95 expression predisposes for recurrence in curatively resected colon carcinoma: clinical evidence for immunoselection and CD95L mediated control of minimal residual disease

    • J Sträter,
    • U Hinz,
    • C Hasel,
    • U Bhanot,
    • G Mechtersheimer,
    • T Lehnert,
    • P Möller
    Gut 2005;54:5 661-665 doi:10.1136/gut.2004.052696

  • Placenta growth factor expression is correlated with survival of patients with colorectal cancer

    • S-C Wei,
    • P-N Tsao,
    • S-C Yu,
    • C-T Shun,
    • J-J Tsai-Wu,
    • C H H Wu,
    • Y-N Su,
    • F-J Hsieh,
    • J-M Wong
    Gut 2005;54:5 666-672 doi:10.1136/gut.2004.050831

Liver

  • Thrombospondin 1 acts as a strong promoter of transforming growth factor β effects via two distinct mechanisms in hepatic stellate cells

    • K Breitkopf,
    • I Sawitza,
    • J H Westhoff,
    • L Wickert,
    • S Dooley,
    • A M Gressner
    Gut 2005;54:5 673-681 doi:10.1136/gut.2004.042911

  • Hepatitis C virus replicates in peripheral blood mononuclear cells of patients with occult hepatitis C virus infection

    • I Castillo,
    • E Rodríguez-Iñigo,
    • J Bartolomé,
    • S de Lucas,
    • N Ortíz-Movilla,
    • J M López-Alcorocho,
    • M Pardo,
    • V Carreño
    Gut 2005;54:5 682-685 doi:10.1136/gut.2004.057281

  • Age and paracetamol self-poisoning

    • L E Schmidt
    Gut 2005;54:5 686-690 doi:10.1136/gut.2004.054619

  • Splanchnic vein thrombosis in candidates for liver transplantation: usefulness of screening and anticoagulation

    • C Francoz,
    • J Belghiti,
    • V Vilgrain,
    • D Sommacale,
    • V Paradis,
    • B Condat,
    • M H Denninger,
    • A Sauvanet,
    • D Valla,
    • F Durand
    Gut 2005;54:5 691-697 doi:10.1136/gut.2004.042796

  • Extrahepatic biliary obstruction after percutaneous tumour ablation for hepatocellular carcinoma: aetiology and successful treatment with endoscopic papillary balloon dilatation

    • N Sasahira,
    • M Tada,
    • H Yoshida,
    • R Tateishi,
    • S Shiina,
    • K Hirano,
    • H Isayama,
    • N Toda,
    • Y Komatsu,
    • T Kawabe,
    • M Omata
    Gut 2005;54:5 698-702 doi:10.1136/gut.2003.038331

Pancreas

  • Antibodies to carbonic anhydrase and IgG4 levels in idiopathic chronic pancreatitis: relevance for diagnosis of autoimmune pancreatitis

    • L Aparisi,
    • A Farre,
    • L Gomez-Cambronero,
    • J Martinez,
    • G De Las Heras,
    • J Corts,
    • S Navarro,
    • J Mora,
    • M Lopez-Hoyos,
    • L Sabater,
    • A Ferrandez,
    • D Bautista,
    • M Perez-Mateo,
    • S Mery,
    • J Sastre
    Gut 2005;54:5 703-709 doi:10.1136/gut.2004.047142

Recent advances in basic science

  • Epidemiology of gastro-oesophageal reflux disease: a systematic review

    • J Dent,
    • H B El-Serag,
    • M-A Wallander,
    • S Johansson
    Gut 2005;54:5 710-717 doi:10.1136/gut.2004.051821

Recent advances in clinical practice

  • Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club

    • F Wong,
    • M Bernardi,
    • R Balk,
    • B Christman,
    • R Moreau,
    • G Garcia-Tsao,
    • D Patch,
    • G Soriano,
    • J Hoefs,
    • M Navasa
    Gut 2005;54:5 718-725 doi:10.1136/gut.2004.038679

JournalScan

Letters

  • Efficacy and strategy of pneumatic dilatation in achalasia

    • R Penagini,
    • P Cantù
    1. Commentator:
      • V F Eckardt
    Gut 2005;54:5 727

  • Probiotics in IBD: mucosal and systemic routes of administration may promote similar effects

    • B Foligné,
    • C Grangette,
    • B Pot
    Gut 2005;54:5 727-728

  • Mutations in anionic trypsinogen gene are not associated with tropical calcific pancreatitis

    • M M Idris,
    • S Bhaskar,
    • D N Reddy,
    • K R Mani,
    • G V Rao,
    • L Singh,
    • G R Chandak
    Gut 2005;54:5 728-729 doi:10.1136/gut.2004.055335

  • Elevated plasma protein C levels correlate with the presence of fatty liver (NASH and NAFLD)

    • N Assy,
    • S Schlesinger,
    • O Hussein
    Gut 2005;54:5 729 doi:10.1136/gut.2004.060251

  • Coexistent chronic idiopathic intestinal pseudo obstruction and inflammatory bowel disease

    • B Ohlsson,
    • F-T Fork,
    • B Veress,
    • E Toth
    Gut 2005;54:5 729-730 doi:10.1136/gut.2004.058826

  • Cannabinoid hyperemesis: not just a problem in Adelaide Hills

    • E Roche,
    • P N Foster
    Gut 2005;54:5 731

  • Inflammatory bowel disease stimulates formation of carcinogenic N-nitroso compounds

    • T M C M de Kok,
    • L G J B Engels,
    • E J Moonen,
    • J C S Kleinjans
    Gut 2005;54:5 731 doi:10.1136/gut.2004.057471

  • Hepatocellular carcinoma occurring after successful treatment of childhood cancer with high dose chemotherapy and radiation

    • T F Greten,
    • M P Manns,
    • I Reinisch,
    • P Kaatsch
    Gut 2005;54:5 732 doi:10.1136/gut.2004.059352

  • Biologics in inflammatory disease: infliximab associated risk of lymphoma development

    • C Bucher,
    • L Degen,
    • S Dirnhofer,
    • M Pless,
    • R Herrmann,
    • P Schraml,
    • P Went
    Gut 2005;54:5 732-733

  • Genotypes 677TT and 677CT+1298AC of methylenetetrahydrofolate reductase are associated with the severity of ulcerative colitis in central China

    • M Chen,
    • B Xia,
    • R M Rodriguez-Gueant,
    • M Bigard,
    • J-L Gueant
    Gut 2005;54:5 733-734 doi:10.1136/gut.2004.062539

CORRECTION

  • CORRECTION

    Gut 2005;54:5 734 doi:10.1136/gut.2004.045294corr1

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