Table 1
Demographic, endoscopic, pH monitoring, histological, and ultrastructural data of the studied population (normal healthy controls, and gastro-oesophageal reflux disease patients with erosive oesophagitis (ERD) and those with a normal appearing oesophageal mucosa (NERD))
| Normal | NERD | ERD | |
|---|---|---|---|
| TEM, transmission electron microscopy. | |||
| No of subjects | 9 | 13 | 13 |
| Sex (M/F) | 4/5 | 4/9 | 7/6 |
| Age (y) (mean (SD) | 38.67 (17.36) | 41.62 (11.77) | 42.54 (13.33) |
| [range] | [26–63] | [22–59] | [25–65] |
| % Time oesophageal pH <4 | 5.42 (1.1) | 9.1 (2.3) | 10.4 (1.9) |
| Endoscopy | |||
| Normal | 9 | 13 | 0 |
| A | 0 | 0 | 0 |
| B | 0 | 0 | 7 |
| C | 0 | 0 | 5 |
| D | 0 | 0 | 1 |
| Histology | |||
| Normal | 9 | 13 | 8 |
| Mild | 0 | 0 | 5 |
| Moderate | 0 | 0 | 0 |
| Severe | 0 | 0 | 0 |
| TEM value (mean (SD)) | 0.54 (0.08) | 2.24 (0.53) | 2.39 (0.44) |
