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Deranged smooth muscle α-actin expression as a biomarker of intestinal pseudo-obstruction
  1. E Jaynes,
  2. N J Carr,
  3. A C Bateman
  1. Department of Cellular Pathology, Southampton General Hospital, Southampton, UK
  1. Correspondence to:
    Dr A C Bateman
    Department of Cellular Pathology, Mailpoint 2, Southampton General Hospital, Level E, South Academic Block, Tremona Road, Southampton SO16 6YD, UK; Adrian.Batemansuht.swest.nhs.uk

https://doi.org/10.1136/gut.2004.062307

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    We read with interest the article by Knowles and colleagues (Gut 2004;53:1583–9) in which the authors concluded that immunostaining of the adult jejunum with smooth muscle α-actin (ASMA) may be a valuable biomarker of chronic idiopathic intestinal pseudo-obstruction (CIIP). We recently published a similar study in which 17 archival formalin fixed, paraffin wax embedded samples of small intestine and 12 samples of large intestine were immunostained with ASMA, desmin, and smooth muscle myosin heavy …

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    Footnotes

    • Conflict of interest: None declared.

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