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Is there an ideal prognostic model for hepatocellular carcinoma?
  1. T-I Huo,
  2. Y-H Huang,
  3. S-D Lee,
  4. J-C Wu
  1. National Yang-Ming University School of Medicine and Taipei Veterans General Hospital, Taipei, Taiwan
  1. Correspondence to:
    Dr T-I Huo
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; tihuovghtpe.gov.tw

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We read with interest the paper by Grieco et al (Gut 2005;54:411–8). It is an elegant study that retrospectively compared the prognostic power among the Okuda, Cancer of the Liver Italian Program (CLIP), and Barcelona Clinic Liver Cancer (BCLC) staging systems for patients with hepatocellular carcinoma (HCC). The authors concluded that BCLC and CLIP were good models for non-surgical HCC, and BCLC had better predictive value compared with the others for patients with early stage HCC. As the CLIP system has been prospectively validated and proposed as the primary staging system for HCC,1 it would be interesting to examine how these commonly …

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  • Conflict of interest: None declared.

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