Van Heel and West (Gut 2006;55:1037–46) published a very complete and up to date review on coeliac disease (CD), dealing very clearly with all aspects of CD, from clinical problems to basic science. In the last paragraph they introduce a very “hot topic”, future therapeutic perspectives of CD, involving immunosuppressive drugs, introduction of non-toxic cereals, development of inhibitors of the enzyme tissue transglutaminase, etc. However, the possibility of introducing drug based therapy for CD brings forth some ethical considerations.

A gluten free diet (GFD) is currently the only available …