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Gut 55:582-583 doi:10.1136/gut.2005.086736
  • Letter

Cytomegalovirus colitis in children with inflammatory bowel disease

  1. B Ghidini1,
  2. M Bellaiche1,
  3. D Berrebi2,
  4. J Viala3,
  5. J P Hugot3,
  6. J F Mougenot4,
  7. A Munck5,
  8. M Peuchmaur6,
  9. J P Cezard7
  1. 1Department of Paediatric Gastroenterology and Nutrition, Assistance Publique Hôpitaux de Paris, Paris, France
  2. 2Pathology Departments, and EA 3102 Paris VII Hôpital Robert Debré, Assistance Publique Hôpitaux de Paris, Paris, France
  3. 3Department of Paediatric Gastroenterology and Nutrition, Assistance Publique Hôpitaux de Paris, Paris, France
  4. 4Department of Paediatric Gastroenterology and Nutrition, and EA 3102 Paris VII Hôpital Robert Debré, Assistance Publique Hôpitaux de Paris, Paris, France
  5. 5Department of Paediatric Gastroenterology and Nutrition, Assistance Publique Hôpitaux de Paris, Paris, France
  6. 6Pathology Departments, and EA 3102 Paris VII Hôpital Robert Debré, Assistance Publique Hôpitaux de Paris, Paris, France
  7. 7Department of Paediatric Gastroenterology and Nutrition, and EA 3102 Paris VII Hôpital Robert Debré, Assistance Publique Hôpitaux de Paris, Paris, France
  1. Correspondence to:
    Professor J P Cezard
    Service de Gastroentérologie, Mucoviscidose, Nutrition Pédiatriques, Hôpital Robert Debré, 48 Bd Sérurier, 75935 Paris Cedex 19, France; jean-pierre.cezard{at}rdb.aphp.fr

    The possible association of cytomegalovirus (CMV) infection with a flare up of inflammatory bowel disease (IBD) in adults is known but no case has been reported in children. Many cases were severe, leading to colectomy, and antiviral treatment was not always efficient. Adult CMV colitis in IBD patients produce symptoms, mimicking a flare up of the disease.1,2,3,4,5,6,7,8,9,10

    We report the cases of six children followed for IBD who presented with relapse of their disease, a concomitant CMV colitis. Five were steroid resistant and one infliximab resistant. Clinical characteristics of the patients and diagnostic criteria and outcome of CMV …