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Gut 55:749-753 doi:10.1136/gut.2005.082909
  • Leading article

The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications

  1. J Satsangi1,
  2. M S Silverberg2,
  3. S Vermeire3,
  4. J-F Colombel4
  1. 1Gastrointestinal Unit, Western General Hospital, University of Edinburgh, Edinburgh, UK
  2. 2Mount Sinai Hospital Inflammatory Bowel Disease Centre, University of Toronto, Toronto, Canada
  3. 3Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
  4. 4Department of Hepatogastroenterology, Hopital Claude Huriez, CHRU Lille, France
  1. Correspondence to:
    Professor J-F Colombel
    Department of Hepato-Gastroenterology, Hopital Claude Huriez, CHRU de Lille, 59037 Lille Cedex, France; jfcolombel{at}chru-lille.fr
  • Accepted 9 January 2006
  • Revised 5 January 2006

Abstract

In recent years, investigators have readdressed the complex issues involved in the classification of inflammatory bowel diseases. In 2003, a Working Party of investigators with an interest in the issues involved in disease subclassification was formed with the aim of summarising recent developments in disease classification and establishing an integrated clinical, molecular, and serological classification of inflammatory bowel disease. The results of the Working Party were reported at the 2005 Montreal World Congress of Gastroenterology. Here we highlight the key issues that have emerged from discussions of the Montreal Working Party and the relevance to clinical practice and research activities.

Footnotes

  • Conflict of interest: None declared.

  • Members of the Working Party

  • Mark S Silverberg MD PhD FRCPC (chair), Department of Medicine, Mount Sinai Hospital IBD Centre, University of Toronto, Toronto, Ontario, Canada; Jack Satsangi DPhil FRCP FRCPE (co-chair), Department of Gastroenterology, Western General Hospital, University of Edinburgh, Edinburgh, UK; Tariq Ahmad MRCP, DPhil, Gastroenterology Unit, University of Oxford, Gibson Laboratories, Radcliffe Infirmary, Oxford, UK; Ian DR Arnott, Department of Gastroenterology, Western General Hospital, University of Edinburgh, Edinburgh, UK; Charles N Bernstein MD, Department of Medicine, Section of Gastroenterology, University of Manitoba IBD Clinical and Research Centre, Winnipeg, Manitoba, Canada; Steven R Brant MD, The Harvey M and Lyn P Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, and Department of Genetic Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Renzo Caprilli MD, Department of Clinical Sciences, University of Rome "La Sapienza", Rome, Italy; Jean-Frédéric Colombel MD, Department of Hepatogastroenterology and Registre EPIMAD, Hôpital HURIEZ, CH et U Lille, France; Christoph Gasche MD, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria; Karel Geboes MD PhD, Department of Pathology, University Hospital, Leuven, Belgium; Derek P Jewell DPhil FRCP, Department of Gastroenterology, University of Oxford, Oxford, UK; Amir Karban MD, Department of Gastroenterology, Rambam Medical Center, Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel; Edward V Loftus Jr MD, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA; A Salvador Peña MD PhD FRCP, Department of Pathology, VU University Medical Centre, Amsterdam, The Netherlands; Robert H Riddell MD, FRCPC FRCPath, Department of Pathology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario; David B Sachar MD FACP MACG, Mount Sinai School of Medicine, New York, New York, USA; Stefan Schreiber MD, Institute for Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany; A Hillary Steinhart MD, Department of Medicine, Mount Sinai Hospital IBD Centre, University of Toronto, Toronto, Ontario, Canada; Stephan R Targan MD, Cedars-Sinai Division of Gastroenterology, Inflammatory Bowel Disease Center and Immunobiology Institute, UCLA School of Medicine, Los Angeles, California, USA; Severine Vermeire MD PhD, Division of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium; Bryan F Warren MB ChB FRCPath, Department of Cellular Pathology, John Radcliffe Hospital, University of Oxford, Oxford, UK