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Gut 55:1363-1364 doi:10.1136/gut.2006.099465
  • Letter

Leukotriene receptor antagonists as potential steroid sparing agents in a patient with serosal eosinophilic gastroenteritis

  1. M C Urek1,
  2. M Kujundžić1,
  3. M Banić1,
  4. R Urek2,
  5. T Š Veić3,
  6. D Kardum4
  1. 1Department of Internal Medicine, Clinical Hospital Dubrava, Zagreb, Croatia
  2. 2Department of Internal Medicine, General Hospital Sveti Duh, Zagreb, Croatia
  3. 3Department of Cytology, Clinical Hospital Dubrava, Zagreb, Croatia
  4. 4Department of Internal Medicine, Clinical Hospital Dubrava, Zagreb, Croatia
  1. Correspondence to:
    Dr M C Urek
    Department of Internal Medicine, Clinical Hospital Dubrava, Domagojeva 9, 10000 Zagreb, Croatia; murek{at}kbd.hr

    Eosinophilic gastroenteritis is a heterogeneous and uncommon disorder characterised by eosinophilic inflammation of the gastrointestinal tissues. The location and depth of infiltration determine its various manifestations and later serve as the basis for its classification as mucosal, muscular, and serosal forms of eosinophilic gastroenteritis. The gold standard for diagnosis is an endoscopic biopsy showing prominent tissue eosinophilia. Gastrointestinal mucosal involvement causes malabsorption, protein losing enteropathy, and diarrhoea. Infiltration of the muscular layer of the bowel wall may cause gastric outlet or small bowel obstruction. Serosal involvement causes exudative ascites rich in eosinophils; this is the least common form and is usually diagnosed by laparoscopic examination and biopsy of the whole intestinal wall. …