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Common pathways in Crohn’s disease and other inflammatory diseases revealed by genomics
  1. Dunecan Massey,
  2. Miles Parkes
  1. IBD Genetics Research Group, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK
  1. Dr M Parkes, IBD Genetics Research Group, Department of Gastroenterology, Box 201A, Addenbrooke’s Hospital, Cambridge, CB2 0QQ, UK; miles.parkes{at}addenbrookes.nhs.uk

Abstract

Genetics may not provide all the answers but it will, in highlighting the pathways relevant to the pathogenesis of Crohn’s disease and other inflammatory conditions, at least indicate which questions need answering

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Footnotes

  • Conflict of interest: None.

  • Abbreviations:
    GWA
    genome-wide association
    IL
    interleukin
    IL23R
    interleukin 23 receptor
    MHC
    major histocompatibility complex
    SNP
    single nucleotide polymorphism
    T1D
    type 1 diabetes
    UC
    ulcerative colitis
    WTCCC
    Wellcome Trust Case Control Consortium

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