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Octreotide LAR for severe obscure-overt gastrointestinal haemorrhage in high-risk patients on anticoagulation therapy
  1. J Molina-Infante,
  2. B Perez-Gallardo,
  3. G Gonzalez-Garcia,
  4. M Fernandez-Bermejo,
  5. J M Mateos-Rodriguez,
  6. P Robledo-Andres
  1. Unit of Gastroenterology, Hospital San Pedro de Alcantara, Caceres, Spain
  1. Correspondence to:
    Dr J Molina-Infante
    Hospital San Pedro de Alcántara, Avda, Pablo Naranjo s/n, 10003 Caceres, Spain; xavi_molina{at}hotmail.com

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We read with interest the letter by Krikis et al (Gut 2005;54:171–2). We report on two patients with a poor clinical history (recurrent gastrointestinal haemorrhage, older age, severe comorbidity, anticoagulation, contraindication to β-blockers), successfully treated using only octreotide long-active release (LAR).

A 73-year-old man was admitted six times (32 days of hospital stay) in the previous six months because of recurrent episodes of melaena. Medical history included type 1 diabetes, three myocardial infarctions and multivessel disease treated by triple-bypass graft surgery (left ventricular ejection fraction 35%), ischaemic stroke due to total occlusion of the right carotid artery, surgically solved, and occlusion of the …

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