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Dissemination of evidence-based clinical practice guidelines for hepatocellular carcinoma among Japanese hepatologists, liver surgeons and primary care physicians
  1. Norihiro Kokudo1,
  2. Yo Sasaki2,
  3. Takeo Nakayama3,
  4. Masatoshi Makuuchi4
  1. 1Department of Surgery, Hepato-Biliary-Pancreatic Surgery Division, Artificial Organ and Transplantation Division, University of Tokyo, Tokyo, Japan
  2. 2Department of Gastrointestinal Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
  3. 3Department of Health Informatics, Kyoto University School of Public Health, Kyoto, Japan
  4. 4Department of Surgery, Hepato-Biliary-Pancreatic Surgery Division, Artificial Organ and Transplantation Division, University of Tokyo, Tokyo, Japan
  1. Correspondence to:
    Professor N Kokudo
    Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan; kokudo-2su{at}h.u-tokyo.ac.jp

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Supported by the Japanese Ministry of Health, Labour and Welfare, the first Clinical practice guidelines for hepatocellular carcinoma (the JHCC guidelines) were compiled in Japan, using an evidence-based methodology. Covering six major research fields for hepatocellular carcinoma (HCC), this set of guidelines consists of 58 pairs of research questions and recommendations, and practical algorithms for the surveillance and treatment of HCC (fig 1).1,2 A complete English translation of the main body of the guidelines has recently been uploaded on the website of The Japanese Society of Hepatology (http://www.jsh.or.jp/). The JHCC guidelines are primarily intended to support both physicians and patients in their decision making on the management of HCC.

Figure 1

 Treatment algorithm for hepatocellular …

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