Article Text

PDF
Authors’ response
  1. D Corley,
  2. A Kubo
  1. Kaiser Permanente, Division of Research, Oakland, California, USA
  1. Dr D Corley, Kaiser Permanente, Division of Research, 12 Jordan Avenue, San Francisco, CA 94118, USA; douglas.corley{at}kp.org

Statistics from Altmetric.com

We thank Drs Rajendra and Robertson for their supplementary commentary, analysis, work and interest in this intriguing field of research. Although their data had somewhat similar results to our case–control study, the critical differences in study design warrant explication.

The associations between Helicobacter pylori, Barrett’s oesophagus and gastro-oesophageal reflux disease (GORD) have been contradictory: some studies have shown no association, some a positive association and some, like the case series by Drs Rajendra and Robertson, suggested an inverse association.13 However, the case series design used by almost all prior studies (which, unfortunately, could not all be cited due to space limitations) are very susceptible to bias, which may have created the conflicting results.

Given this knowledge, we used a community-based case–control design to attempt a less biased estimate of the association between H pylori …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles