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Funding: WS has received research support from and has served as a consultant for Abbott Laboratories, Centocor, Schering Plough and UCB Pharma, and has participated in continuing medical education events indirectly sponsored by Abbott Laboratories, Centocor, Schering Plough and UCB Pharma.
Competing interests: Declared (the declaration can be viewed on the Gut website at http://gut.bmj.com/content/vol57/issue4).