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Latent coeliac disease in childhood?
  1. Reynella A Morenas1,
  2. Mark P Tighe1,
  3. Isabella Moore2,
  4. Nadeem A Afzal1,
  5. R Mark Beattie1
  1. 1 Paediatric Medical Unit, Southampton University Hospitals NHS Trust, Southampton, UK
  2. 2 Southampton University Hospitals NHS Trust, Department of Cellular Pathology, Southampton General Hospital, Southampton, UK
  1. Dr R Mark Beattie, Paediatric Medical Unit, Southampton General Hospital, Tremona Rd, Southampton SO16 6YD, UK; mark.beattie{at}suht.swest.nhs.uk

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We read with interest the paper by Matysiak-Budnik et al (Gut 2007;56:1379–86) reporting the development of true latency or tolerance to gluten in adulthood. We would like to report a recent case of apparent serological and histological resolution of coeliac disease in childhood.

In 2001 a 5-year-old girl presented with a 6-month history of recurrent abdominal pain. She had been previously well. There was no past history of food intolerance or family history of coeliac disease. She was found to be iron deficient on examination. Endomysial antibodies were strongly positive and a duodenal biopsy was entirely consistent with coeliac disease (fig 1). She was commenced on a gluten-free diet, which she adhered to for at least 6 months. …

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