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We read with great interest the article by Sandborn et al (Gut 2007;56:1232–9) about maintenance therapy of Crohn’s disease with adalimumab and the recent publication by Viget et al (Gut 2008;57:549–58) on opportunistic infections in patients with inflammatory bowel disease. In their series including 276 patients, Sandborn et al note no severe infectious complications apart from upper respiratory tract infections. It is noteworthy that no cases of aspergillosis or other opportunistic infections were reported.
Unfortunately, serious infections are a well known problem of tumour necrosis factor α (TNFα) antibody therapies. Here, we present a case report of a 69-year-old female patient with a long history of stenosing Crohn’s disease. The patient …
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