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Gut 58:97-103 doi:10.1136/gut.2008.149179
  • Pancreas

The natural history of hereditary pancreatitis: a national series

Table 4 Indications of specific treatment
Characteristic All patients (n = 200) Patients with PRSS1 mutations (n = 135) Patients without detected PRSS1 mutation (n = 65†) p Value
Chronic use of analgesics (%)* (md = 2) 20 (10) 14 6 NS
Endoscopic treatment (%) (md = 3) 31 (16) 24 7 NS
Surgical treatment (%) (md = 1) 49 (24) 39 10 NS
  • *At least one period of chronic use >3 months.

  • †Including nine patients deceased before 1996, in whom PRSS1 mutation could not be searched for.

  • md, Missing data; NS, not significant; PRSS1, cationic trypsinogen gene.

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