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Applicability of BARD score to Japanese patients with NAFLD
  1. H Fujii1,
  2. M Enomoto1,
  3. W Fukushima2,
  4. A Tamori1,
  5. H Sakaguchi1,
  6. N Kawada1
  1. 1
    Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan
  2. 2
    Department of Public Health, Graduate School of Medicine, Osaka City University, Osaka, Japan
  1. Correspondence to Dr N Kawada, Department of Hepatology, Graduate School of Medicine, Osaka City University, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan; kawadanori{at}med.osaka-cu.ac.jp

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We read the article by Harrison et al1 with great interest. The authors proposed an easily calculated composite score for predicting the risk of advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD), called the BARD score: the weighted sum of the three variables (body mass index (BMI) ⩾28 = 1 point, aspartate aminotransferase/alanine aminotransferase ratio (AAR) ⩾0.8 = 2 points, diabetes = 1 point). When a BARD score of 2–4 was used, the area under the receiver operating characteristic curve (AUROC) was found to be 0.81 with an odds ratio (OR) of 17 (95% CI 9.2 to 31.9) for detecting advanced fibrosis. The positive predictive value (PPV) and negative predictive value (NPV) were 43% and 96%, respectively. We studied the reliability of the BARD score for identifying …

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