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Haemoglobin and non-alcoholic fatty liver disease: further evidence from a population-based study
  1. L Xu1,2,
  2. C-f Xu2,
  3. C-h Yu2,
  4. M Miao3,
  5. Y-m Li2
  1. 1
    Department of Gastroenterology, Ningbo No. 1 Hospital, Ningbo, China
  2. 2
    Department of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
  3. 3
    Department of Internal Medicine, The Hospital of Zhenhai Refining & Chemical Company, Ningbo, China
  1. Correspondence to Dr Y-m Li, Department of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China; xiaofu{at}zju.edu.cn

https://doi.org/10.1136/gut.2009.186668

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    We read with great interest the article by Trak-Smayra and colleagues1 showing that serum free haemoglobin subunits correlated positively with severity of liver lesions in non-alcoholic fatty liver disease (NAFLD) and may serve as a biomarker for the disease. However, the detail relationship between serum haemoglobin concentrations and NAFLD has not been clearly clarified.

    Recently, we conducted a cross-sectional study to analysis the association of serum haemoglobin concentration with NAFLD. We included 8985 employees (6101 men, mean age 45.7 years) of the Zhenhai Refining & Chemical Company Ltd. (Ningbo, China) who were attending their annual health examination …

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    Footnotes

    • Funding This study was supported by Chinese State Key Project for High-tech (No. 2006AA02A308), National Natural Science Foundation of China (No. 30871154) and Science and Technology Foundation of Zhejiang Province (No. 2008C13027-1).

    • Competing interests None.

    • Provenance and peer review Not commissioned; not externally peer reviewed.

    • LX and C-f Xu contributed equally to this work.