Table 3 Effect of vascular endothelial growth factor receptor 2 (VEGFR2) blockade on vascular leakage in cirrhotic rats with ascites
| Tissue | Cirrhotic rats (n = 5) | Cirrhotic rats + SU11248 (n = 5) |
| Liver | 148.2 (20.9) | 59.7 (5.3)** |
| Mesentery | 13.4 (2.2) | 6.0 (1.0)* |
| Pancreas | 10.1 (2.9) | 17.9 (3.6) |
| Spleen | 120.4 (12.4) | 155.0 (21.2) |
| Small intestine | 17.1 (2.9) | 14.9 (2.5) |
| Kidney | 118.3 (27.9) | 65.3 (23.0) |
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Results (mean (SE)) are given for the regional vascular permeability (μg Evan’s Blue per g tissue).
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*p<0.01 and **p<0.001 vs control rats.
