Table 12
Summary of human studies investigating antineoplastic effects of resistant starch
| Author | Study subjects | Type, dose and duration of RS treatment | Effect of RS |
| Van Muster et al3 | 14 healthy subjects | 45 g Hylon VII (32%) or 20 g RS low natural fibre | ↓Cell proliferation, ↑SCFA and butyrate, ↓bile acids |
| Grubben et al15 | 23 patients with recently removed colonic adenomas | 45 g amylomaize (28 g RS)/day or 45 g maltodextrin | Cell proliferation NSD, ↑butyrate |
| Van Gorkom et al16 | 111 sporadic adenoma patients | 30 g Hylon VII (19 g RS) or 30 g of placebo starch | Cell proliferation NSD |
| Wacker et al17 | 12 healthy subjects | Hylon VII (50.7–59.7 g/day) or low RS corn starch | Cell proliferation NSD, ↑DNA adducts, ↑SCFA |
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NSD, non-significant difference; RS, resistant starch; SCFA, short chain fatty acid.
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↑ indicates an increase; ↓ indicates a decrease.
