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Fast-food hyper-alimentation and exercise restriction in healthy subjects
  1. R D Johnston1,
  2. G P Aithal1,
  3. S D Ryder1,
  4. I A MacDonald2
  1. 1
    Wolfson Digestive Diseases Centre, University Hospital, Nottingham, UK
  2. 2
    School of Biomedical Sciences, University of Nottingham Medical School, Nottingham, UK
  1. Dr R D Johnston, Wolfson Digestive Diseases Centre, University Hospital, Nottingham, NG7 2UH, UK; rjohnston75{at}doctors.org.uk

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We read with great interest the recent article by Kechegias et al on the hepatic effects of fast-food hyper-alimentation and exercise restriction (Gut 2008;57:649–54). The metabolic effects of fast-food consumption are a major public health issue, and have recently resulted in demands for the energy and nutrient content labelling of fast-food menus.1 Fast-food consumers significantly underestimate the energy and fat content of fast-foodstuffs, and their consumptive behaviours alter when they are informed of the foodstuffs’ true content.2

We would first like to commend them on performing such a valuable study. We agree with their conclusion that a dietary, as well as an alcohol history is an imperative component of the evaluation of patients with an idiopathically elevated alanine aminotransferase (ALT). Our …

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