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We congratulate Zagari et al on their recent paper (Gut 2008;57:1354–9) in which they report the prevalence of gastroesophageal reflux disease and Barrett’s oesophagus in the Italian population. Such population-based studies are very rare and very valuable.
It is well established that oesophageal adenocarcinoma and Barrett’s oesophagus, complications of severe reflux disease, are much more common in males than females. …