Table 2 Changes in the gut microbiota upon administration of prebiotics impacts on portal plasma gut peptides
| Gut peptide | Ob-CT | Ob-Cell | Ob-Pre |
| GLP-1 (active) (pmol/l) | 7.65a (1.52) | 7.71a (1.62) | 21.15b (6.71) |
| GIP (total) (pg/ml) | 207.91a (37.76) | 180.71a (27.53) | 114.02b (16.92) |
| Pancreatic polypeptide (pg/ml) | 68.07a (8.45) | 75.94a (6.56) | 50.05b (2.67) |
| Amylin (active) (pg/ml) | 358.87a (36.12) | 364.99a (45.07) | 504.90b (58.34) |
| GLP-2 (ng/ml) | 0.56a (0.06) | 0.62a (0.04) | 0.75b (0.05) |
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Data are mean (SEM).
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Data with different superscript letters are significantly different at p<0.05, according to the post hoc ANOVA statistical analysis.
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CT, Cell and Pre, respectively, refer to the selected ob/ob mice, fed a normal diet, non-prebiotic control diet or prebiotic diet. GIP, glucose-dependent insulinotropic polypeptide; GLP, glucogon-like peptide.
